Bacterial Vaginosis

Recommended Regimen

Metronidazole 500 mg orally 2 times/day for 7 days


Metronidazole gel 0.75% one full applicator (5 g) intravaginally, once daily for 5 days


Clindamycin cream 2% one full applicator (5 g) intravaginally at bedtime for 7 days

Alternative Regimen

Clindamycin 300 mg orally 2 times/day for 7 days


Clindamycin ovules 100 mg intravaginally once at bedtime for 3 days*


Secnidazole 2 g oral granules in a single dose†


Tinidazole 2 g orally once daily for 2 days or Tinidazole 1 g orally once daily for 5 days

* Clindamycin ovules use an oleaginous base that might weaken latex or rubber products (e.g., condoms and diaphragms). Use of such products within 72 hours after treatment with clindamycin ovules is not recommended.

† Oral granules should be sprinkled onto unsweetened applesauce, yogurt, or pudding before ingestion. A glass of water can be taken after administration to aid in swallowing.

Page last reviewed: July 16, 2021
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