Epididymitis

For acute epididymitis most likely caused by chlamydia or gonorrhea:  

Ceftriaxone 500 mg* IM in a single dose  

PLUS 

Doxycycline 100 mg orally 2 times/day for 10 days  

* For persons weighing ≥150 kg, 1 g of ceftriaxone should be administered.

For acute epididymitis most likely caused by chlamydia, gonorrhea, or enteric organisms (men who practice insertive anal sex):  

Ceftriaxone 500 mg* IM in a single dose  

PLUS 

Levofloxacin 500 mg orally once daily for 10 days  

* For persons weighing ≥150 kg, 1 g of ceftriaxone should be administered.

For acute epididymitis most likely caused by enteric organisms only:                   

Levofloxacin 500 mg orally once daily for 10 days 

None