Granuloma Inguinale (Donovanosis)

Recommended Regimen

Azithromycin 1 g orally once weekly or 500 mg daily for >3 weeks and until all lesions have completely healed

Alternative Regimen

Doxycycline 100 mg orally 2 times/day for at least 3 weeks and until all lesions have completely healed

OR

Erythromycin base 500 mg orally 4 times/day for >3 weeks and until all lesions have completely healed

OR

Trimethoprim-sulfamethoxazole one double-strength (160 mg/800 mg) tablet orally 2 times/day for >3 weeks and until all lesions have completely healed

Page last reviewed: July 16, 2021
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