Table 21. Congenital Syphilis — Reported Cases and Rates of Reported Cases by Year of Birth, by State/Territory* and Region in Alphabetical Order, United States, 2017–2021

Table 21. Congenital Syphilis — Reported Cases and Rates of Reported Cases by Year of Birth, by State/Territory* and Region in Alphabetical Order, United States, 2017–2021
State/Territory Cases Rates per 100,000 Population
2017 2018 2019 2020 2021 2017 2018 2019 2020 2021
Alabama 6 7 15 21 37 10.2 12.1 25.6 36.4 63.7
Alaska 0 1 0 8 5 0.0 9.9 0.0 84.5 53.4
Arizona 32 61 109 121 181 39.1 75.6 137.3 157.3 232.3
Arkansas 8 25 21 23 50 21.3 67.5 57.4 65.2 139.0
California 281 329 444 481 518 59.6 72.3 99.4 114.5 123.2
Colorado 4 8 10 22 30 6.2 12.7 15.9 35.8 47.7
Connecticut 0 2 3 2 6 0.0 5.8 8.8 6.0 16.8
Delaware 0 0 2 2 1 0.0 0.0 18.9 19.2 9.5
District of Columbia 0 1 1 3 6 0.0 10.9 11.0 33.8 69.3
Florida 99 109 145 154 180 44.3 49.2 65.9 73.4 83.2
Georgia 23 31 56 81 93 17.8 24.6 44.3 66.1 75.0
Hawaii 3 4 3 12 20 17.1 23.6 17.9 76.0 128.0
Idaho 0 1 1 2 5 0.0 4.7 4.5 9.3 22.3
Illinois 22 30 32 29 50 14.7 20.7 22.8 21.8 37.8
Indiana 8 1 13 8 20 9.7 1.2 16.1 10.2 25.0
Iowa 2 3 1 1 11 5.2 7.9 2.7 2.8 29.9
Kansas 1 8 9 8 7 2.7 22.1 25.4 23.3 20.2
Kentucky 6 9 9 13 25 11.0 16.7 17.0 25.2 47.9
Louisiana 57 43 68 63 110 93.4 72.1 115.4 109.9 191.5
Maine 0 0 0 0 0 0.0 0.0 0.0 0.0 0.0
Maryland 20 29 32 31 NR 27.9 40.8 45.6 45.2
Massachusetts 0 0 9 10 9 0.0 0.0 13.0 15.1 13.0
Michigan 10 14 17 29 42 9.0 12.7 15.8 27.9 40.0
Minnesota 2 10 21 7 15 2.9 14.8 31.8 11.0 23.3
Mississippi 1 3 3 37 64 2.7 8.1 8.2 104.3 182.0
Missouri 10 18 18 32 66 13.7 24.6 25.0 46.2 95.0
Montana 1 0 1 2 9 8.5 0.0 9.0 18.5 80.1
Nebraska 1 0 0 1 1 3.9 0.0 0.0 4.1 4.1
Nevada 24 31 41 46 45 67.1 86.9 116.9 136.7 133.6
New Hampshire 0 1 2 0 0 0.0 8.3 16.9 0.0 0.0
New Jersey 14 13 15 24 48 13.8 12.8 15.1 24.5 47.3
New Mexico 1 10 28 42 44 4.2 43.4 122.0 191.8 205.7
New York 16 28 27 30 41 7.0 12.4 12.2 14.3 19.5
North Carolina 25 19 27 31 42 20.8 16.0 22.7 26.6 34.9
North Dakota 0 0 0 3 2 0.0 0.0 0.0 29.8 19.8
Ohio 18 21 19 33 51 13.2 15.5 14.1 25.5 39.3
Oklahoma 7 11 42 52 85 13.9 22.1 85.5 109.2 175.6
Oregon 8 10 18 19 27 18.3 23.7 43.0 47.7 66.0
Pennsylvania 7 9 13 15 14 5.1 6.6 9.7 11.5 10.6
Rhode Island 0 0 0 1 2 0.0 0.0 0.0 9.9 19.1
South Carolina 8 9 17 19 19 14.0 15.9 29.8 34.1 33.2
South Dakota 3 1 2 4 16 24.7 8.4 17.5 36.5 140.7
Tennessee 10 13 13 31 39 12.3 16.1 16.2 39.4 47.7
Texas 179 371 528 561 680 46.9 98.0 139.8 152.4 182.0
Utah 0 1 4 1 2 0.0 2.1 8.5 2.2 4.3
Vermont 0 0 0 0 1 0.0 0.0 0.0 0.0 18.6
Virginia 12 10 11 15 18 12.0 10.0 11.3 15.8 18.8
Washington 6 6 17 10 53 6.9 7.0 20.0 12.0 63.2
West Virginia 3 1 6 9 15 16.1 5.5 33.1 52.0 87.2
Wisconsin 3 1 2 7 15 4.6 1.6 3.2 11.6 24.3
Wyoming 0 0 0 1 0 0.0 0.0 0.0 16.3 0.0
US TOTAL 941 1,313 1,875 2,157 2,855 24.4 34.6 50.0 59.7 77.9
   Northeast 37 53 69 82 121 6.0 8.7 11.5 14.2 20.5
   Midwest 80 107 134 162 296 9.9 13.4 17.1 21.5 38.9
   South 464 691 996 1,146 1,499 30.9 46.5 67.4 79.8 102.6
   West 360 462 676 767 939 38.9 51.4 76.2 90.6 110.1
American Samoa NR 0 0 0 0 0.0 0.0 0.0 0.0
Commonwealth of the Northern Mariana Islands NR 0 0 0 0 0.0 0.0 0.0 0.0
Guam 0 0 0 0 1 0.0 0.0 0.0 0.0 38.1
Puerto Rico 7 9 7 5 9 28.8 42.0 34.4 26.4 46.6
Virgin Islands 0 NR 0 0 0 0.0 0.0 0.0 0.0
TERRITORIES TOTAL 7 9 7 5 10 24.3 34.5 26.8 20.7 41.4
TOTAL 948 1,322 1,882 2,162 2,865 24.4 34.6 49.9 59.4 77.7
* Mother’s state/territory of residence was used to assign case.

NR = No report.

NOTE: See Technical Notes for more information on interpreting case counts and rates in US territories. The COVID-19 pandemic has introduced uncertainty and difficulty in interpreting STD data collected during 2020 and 2021. See Impact of COVID-19 on STDs for more information. Due to a network security incident in December 2021, the Maryland Department of Health could not finalize their 2021 STD case notification data. Although 2021 data from Maryland are included in national and regional case counts and rates displayed in this table, state-specific data have been suppressed.

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