Table 13. Primary and Secondary Syphilis — Reported Cases and Rates of Reported Cases by State, Ranked by Rates, United States, 2021

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Table 13. Primary and Secondary Syphilis — Reported Cases and Rates of Reported Cases by State, Ranked by Rates, United States, 2021
Rank* State Cases Rate per 100,000 Population
1 South Dakota 436 48.7
2 New Mexico 724 34.2
3 Arkansas 990 32.7
4 Oklahoma 1,225 30.7
5 Nevada 939 29.9
6 Mississippi 829 28.1
7 Arizona 1,982 27.2
8 Alaska 194 26.5
9 Oregon 949 22.3
10 California 8,724 22.2
11 Louisiana 995 21.5
12 Missouri 1,316 21.3
13 Florida 4,498 20.7
14 Washington 1,506 19.5
15 Rhode Island 209 19.1
16 Hawaii 259 18.0
17 North Carolina 1,870 17.7
18 New York 3,500 17.6
19 Georgia 1,884 17.4
US TOTAL† 53,767 16.2
20 South Carolina 836 16.1
21 Ohio 1,783 15.1
22 Alabama 761 15.1
23 Tennessee 952 13.6
24 Colorado 772 13.3
25 Texas 3,865 13.1
26 Delaware 129 12.9
27 Wisconsin 723 12.3
28 West Virginia 212 11.9
29 Illinois 1,486 11.7
30 Kentucky 513 11.4
31 Indiana 734 10.8
32 Iowa 339 10.6
33 Massachusetts 741 10.6
34 Kansas 301 10.3
35 Pennsylvania 1,310 10.1
36 Minnesota 565 9.9
37 New Jersey 908 9.8
38 Michigan 972 9.7
39 Nebraska 185 9.4
40 Connecticut 329 9.1
41 Montana 96 8.7
42 Virginia 745 8.6
43 North Dakota 49 6.3
44 Utah 205 6.1
45 New Hampshire 73 5.3
46 Maine 61 4.4
47 Idaho 84 4.4
48 Wyoming 16 2.8
49 Vermont 9 1.4
Maryland NR —
 

* States were ranked by rate, then case count, then in alphabetical order, with rates shown rounded to the nearest tenth.

† Total includes cases reported by the District of Columbia with 257 cases and a rate of 38.4, but excludes territories.

NR = No report.

NOTE: The COVID-19 pandemic has introduced uncertainty and difficulty in interpreting STD data collected during 2020 and 2021. See Impact of COVID-19 on STDs for more information. Due to a network security incident in December 2021, the Maryland Department of Health could not finalize their 2021 STD case notification data. Although 2021 data from Maryland are included in the national case count and rate displayed in this table, state-specific data have been suppressed.

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