Table 12. Total Syphilis* — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States, 2017–2021

Table 12. Total Syphilis* — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States, 2017–2021
State/Territory Cases Rates per 100,000 Population
2017 2018 2019 2020 2021 2017 2018 2019 2020 2021
Alabama 1,202 1,285 1,634 1,518 2,173 24.7 26.3 33.3 30.2 43.1
Alaska 28 113 242 361 447 3.8 15.3 33.1 49.2 61.0
Arizona 2,424 3,249 4,022 4,461 6,330 34.5 45.3 55.3 62.4 87.0
Arkansas 726 964 1,106 1,243 2,403 24.2 32.0 36.6 41.3 79.4
California 21,804 25,253 28,811 26,414 31,276 55.1 63.8 72.9 66.8 79.7
Colorado 817 1,085 1,434 1,785 2,303 14.6 19.0 24.9 30.9 39.6
Connecticut 283 264 482 536 888 7.9 7.4 13.5 14.9 24.6
Delaware 194 129 216 222 295 20.2 13.3 22.2 22.4 29.4
District of Columbia 845 764 1,085 988 870 121.8 108.8 153.7 143.3 129.8
Florida 8,957 10,701 12,121 12,416 16,438 42.7 50.2 56.4 57.6 75.5
Georgia 4,310 4,928 5,683 5,595 6,711 41.3 46.8 53.5 52.2 62.1
Hawaii 165 210 252 397 643 11.6 14.8 17.8 27.3 44.6
Idaho 151 134 149 184 270 8.8 7.6 8.3 10.0 14.2
Illinois 3,838 4,472 4,511 4,568 5,124 30.0 35.1 35.6 35.7 40.4
Indiana 788 985 993 1,349 1,980 11.8 14.7 14.7 19.9 29.1
Iowa 290 286 359 501 763 9.2 9.1 11.4 15.7 23.9
Kansas 339 495 565 539 803 11.6 17.0 19.4 18.3 27.4
Kentucky 722 881 1,096 1,143 1,559 16.2 19.7 24.5 25.4 34.6
Louisiana 2,854 2,744 2,744 2,497 3,480 60.9 58.9 59.0 53.6 75.3
Maine 132 147 136 81 135 9.9 11.0 10.1 5.9 9.8
Maryland 2,059 2,536 2,779 2,683 NR 34.0 42.0 46.0 43.4
Massachusetts 1,474 1,305 1,844 1,658 2,051 21.5 18.9 26.8 23.6 29.4
Michigan 1,267 1,692 1,905 2,059 2,671 12.7 16.9 19.1 20.4 26.6
Minnesota 934 918 1,127 1,098 1,465 16.7 16.4 20.0 19.2 25.7
Mississippi 937 1,454 2,006 2,131 2,605 31.4 48.7 67.4 72.0 88.3
Missouri 1,337 1,914 2,188 2,333 3,780 21.9 31.2 35.7 37.9 61.3
Montana 85 104 140 101 225 8.1 9.8 13.1 9.3 20.4
Nebraska 118 219 291 268 471 6.1 11.4 15.0 13.7 24.0
Nevada 1,684 2,000 2,356 2,218 3,065 56.2 65.9 76.5 71.4 97.5
New Hampshire 109 137 135 120 145 8.1 10.1 9.9 8.7 10.4
New Jersey 1,867 1,777 2,085 2,385 3,389 20.7 19.9 23.5 25.7 36.6
New Mexico 510 812 1,294 1,496 2,069 24.4 38.8 61.7 70.6 97.8
New York 9,877 10,183 10,500 10,613 13,105 49.8 52.1 54.0 52.5 66.1
North Carolina 2,949 2,989 3,369 3,714 5,029 28.7 28.8 32.1 35.6 47.7
North Dakota 78 84 97 91 106 10.3 11.1 12.7 11.7 13.7
Ohio 1,900 1,909 2,005 2,457 3,958 16.3 16.3 17.2 20.8 33.6
Oklahoma 953 1,137 1,749 1,888 3,003 24.2 28.8 44.2 47.7 75.3
Oregon 848 1,032 1,245 1,320 2,010 20.5 24.6 29.5 31.2 47.3
Pennsylvania 2,235 2,414 2,764 2,898 3,816 17.5 18.8 21.6 22.3 29.4
Rhode Island 221 284 423 315 567 20.9 26.9 39.9 28.7 51.8
South Carolina 1,096 1,152 1,306 1,681 2,079 21.8 22.7 25.4 32.8 40.1
South Dakota 75 74 86 128 924 8.6 8.4 9.7 14.4 103.2
Tennessee 1,453 1,726 2,226 2,463 3,180 21.6 25.5 32.6 35.6 45.6
Texas 12,127 12,973 12,657 15,358 21,476 42.8 45.2 43.7 52.7 72.7
Utah 299 423 431 351 531 9.6 13.4 13.4 10.7 15.9
Vermont 26 29 24 23 16 4.2 4.6 3.8 3.6 2.5
Virginia 1,758 2,039 2,071 1,953 2,205 20.8 23.9 24.3 22.6 25.5
Washington 1,751 1,911 2,186 2,079 3,366 23.6 25.4 28.7 27.0 43.5
West Virginia 124 185 277 407 536 6.8 10.2 15.5 22.7 30.1
Wisconsin 551 509 569 835 1,615 9.5 8.8 9.8 14.2 27.4
Wyoming 19 42 42 32 43 3.3 7.3 7.3 5.5 7.4
US TOTAL 101,590 115,052 129,818 133,954 176,713 31.2 35.2 39.5 40.4 53.2
   Northeast 16,224 16,540 18,393 18,629 24,112 28.7 29.5 32.9 32.3 42.2
   Midwest 11,515 13,557 14,696 16,226 23,660 16.9 19.8 21.5 23.5 34.4
   South 43,266 48,587 54,125 57,900 76,363 35.0 38.9 43.1 45.9 60.0
   West 30,585 36,368 42,604 41,199 52,578 39.5 46.6 54.4 52.4 66.8
American Samoa NR 0 0 0 0 0.0 0.0 0.0 0.0
Commonwealth of the Northern Mariana Islands NR 2 2 2 2 3.8 3.8 3.9 3.9
Guam 21 30 31 21 22 12.5 17.9 18.4 12.5 13.0
Puerto Rico 1,055 1,089 949 829 1,132 31.5 33.1 29.7 25.2 34.7
Virgin Islands 0 NR 45 40 42 0.0 42.2 37.6 39.7
TERRITORIES TOTAL 1,076 1,121 1,027 892 1,198 29.7 31.4 28.8 24.4 32.9
TOTAL 102,666 116,173 130,845 134,846 177,911 31.2 35.1 39.4 40.2 53.0
* See Technical Notes for definition and more information on interpreting case counts and rates in US territories.

NR = No report.

NOTE: The COVID-19 pandemic has introduced uncertainty and difficulty in interpreting STD data collected during 2020 and 2021. See Impact of COVID-19 on STDs for more information. Due to a network security incident in December 2021, the Maryland Department of Health could not finalize their 2021 STD case notification data. Although 2021 data from Maryland are included in national and regional case counts and rates displayed in this table, state-specific data have been suppressed.

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