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Skin Notation Strategy

April 2010
NIOSH Docket Number 153-A

Historically, skin notations have been published in the NIOSH Pocket Guide to Chemical Hazards. This practice will continue with the NIOSH skin notation assignments for each evaluated chemical being integrated as they become available. A support document called a Skin Notation Profile has been developed for each evaluated chemical. The Skin Notation Profile for a chemical is intended to provide information supplemental to the skin notation, including a summary of all relevant data used to aid in determining the hazards associated with skin exposures.

NIOSH obtained comments on the draft skin notation assignments and Skin Notation Profiles for 22 chemicals. The submissions are listed below.

Note: To view the final Skin Notation Profiles visit the Skin Notation Profiles website .

Background Information

Revised Final Document: NIOSH Current Intelligence Bulletin (CIB): 61: A strategy for Assigning New NIOSH Skin Notations – 8/1/17 [PDF – 2 MB]

Final document: NIOSH Current Intelligence Bulletin (CIB) 61: A Strategy for Assigning New NIOSH Skin Notations; 2009-147 – 7/1/09

Peer reviewer summary of comments – 06/01/10 [PDF – 3,712 KB]

Notice of public comment period; 75 FR 22148 – 04/27/10 [PDF – 3,628 KB]

Charge to Reviewers – 04/27/10 [PDF – 1,287 KB]

Peer Reviewer Submissions on 22 Chemicals (in Numerical Order)

Submissions in Numerical Order

Submission to Docket Office from Kristy Morrison (American Chemistry Council) on A-03; 06/11/10 [PDF – 2,153 KB]

Submission to Docket Office from Markku Huvienen and Grant Darrie (International Chromium Development Association) on A-07; 05/12/10 [PDF – 2,941 KB]

Submission to Docket Office from John Wittenborn (Counsel to the Specialty Steel Industry of North American) on A-07; 06/10/10 [PDF – 2,443 KB]

Submission to Docket Office from Paul Dugard (Halogenated Solvents Industry Alliance Inc) on A-18; w/3 attachments; 06/11/10 [PDF – 1,922 KB]

Attachment 1-HLA-B*1301 as a Biomarker for Genetic Susceptibility to Hypersensitivity Dermatitis Induced by Trichloroethylene among Workers in China;11/01/07 [PDF – 5,507 KB]

Attachment 2-Hepatitis, Rash and Eosinophilia Following Trichloroethylene Exposure: A Case Report and Speculation on Mechanistic Similarity to Halothane Induced Hepatitis;01/01/96 [PDF – 5,946 KB]

Attachment 3-Occupational Trichloroethylene Exposure as a Cause of Idiosyncratic Generalized Skin Disorders and Accompanying Hepatitis Similar to Drug Hypersensitivities;01/01/0 [PDF – 16,005 KB]