Skin Notation Strategy

September 2008
NIOSH Docket Number 153

The Current Intelligence Bulletin 61: “A Strategy for Assigning New NIOSH Skin Notations.” CIB 61 provides the rationale and scientific logic behind the development of a strategy for the assignment of hazard-specific skin notations (SK) capable of clearly distinguishing between the systemic, direct and immune-mediated health effects caused by skin contact to chemicals. A public meeting was held on November 6, 2008, to discuss and obtain comments on the draft. Comments were received from NIOSH stakeholders, other governmental agencies, and the public. The final version of the document reflects NIOSH responses to the comments.

Note: To view the final Skin Notation Profiles visit the Skin Notation Profiles website .

Material Under Evaluation

Revised Final Document: NIOSH Current Intelligence Bulletin (CIB) 61: A strategy for Assigning New NIOSH Skin Notations – 8/1/17 [PDF – 2 MB]

Final document: NIOSH Current Intelligence Bulletin (CIB) 61: A Strategy for Assigning New NIOSH Skin Notations; 2009-147 – 7/1/09 [PDF – 40.23 MB]

NIOSH comments to peer reviewers submissions – 4/9/09 [PDF – 7.74 MB]

NIOSH comments to submissions – 4/9/09 [PDF – 7.88 MB]

Draft Current Intelligence Bulletin (CIB): A Strategy for Assigning the New NIOSH Skin Notations for Chemicals – 09/02/08 [PDF – 15,390 KB]

Notice of Public Meeting and availability for Public Comment; 73 FR 54828 – 09/23/08 [PDF – 1,750 KB]

Letter to Peer Reviewers – 10/02/08 [PDF – 1,210 KB]

Submissions from the Public in Order of Receipt

Submission to the docket from Levine (Product Safety Solutions) – 10/14/08 [PDF – 1,350 KB]

Submission to the docket from Borman (State Compensation Insurance Fund) – 10/22/08 [PDF – 335 KB]

Submission to the docket from Borman (State Compensation Insurance Fund) – 10/24/08 [PDF – 240 KB]

Submission to the docket from Sobier-Maier (Technische Universitat Berlin) – 10/24/08 [PDF – 193 KB]

Submission to the docket from Perry (Occupational Safety and Health Administration (OSHA) – 11/06/08 [PDF – 2,850 KB]

Submission to the docket from Ripple (Dow Chemical) – 11/18/08 [PDF – 739 KB]

Submission to the docket from Malley (DuPont Haskell) – 11/19/08 [PDF – 204 KB]

Submission to the docket from Peer Reviewer (2) – 11/21/08 [PDF – 204 KB]

Submission to the docket from Peer Reviewer (1) – 11/23/08 [PDF – 864 KB]

Submission to the docket from Peer Reviewer (3) – 11/25/08 [PDF – 440 KB]

Submission to the docket from Peer Reviewer (4) – 12/01/08 [PDF – 1,210 KB]

Submission to the docket from Peer Reviewer (4) – 12/04/08 [PDF – 14,860 KB]

Peer review

Title: Current Intelligence Bulletin 61: A Strategy for Assigning New NIOSH Skin Notations

Subject: This CIB provides a new NIOSH strategy for assigning skin notations for workplace chemicals that are dermal hazards.

Purpose: To explain a new strategic framework for assigning multiple skin notations which incorporates the current scientific knowledge on workplace chemicals and dermal toxicity to distinguish between direct, systemic, and sensitizing effects of exposures of the skin to chemicals.

Timing of Review: Summer 2008

Primary Disciplines or Expertise Needed for Review: Chemistry, toxicology, industrial hygiene, epidemiology, risk assessment

Type of Review: Individual

Number of Reviewers: 4

Reviewers Selected by: NIOSH

Public Nominations Requested for Reviewers: No

Opportunities for the Public to Comment: Yes

Peer Reviewers Provided with Public Comments Before Their Review: Yes

Peer Reviewers:

John Cherrie, Ph.D.
Research Director, Institute of Occupational Medicine
Recommended by: NIOSH

Richard Fenske, Ph.D., M.A., M.P.H.
Associate Chair and Professor, Department of Environmental and Occupational Health Sciences, School of Public Health and Community Medicine, University of Washington
Recommended by: NIOSH

Youcheng Liu, M.D., Sc.D., M.P.H.
Assistant Professor, Department of Preventive Medicine and Environmental Health, College of Public Health, University of Kentucky
Recommended by: NIOSH

Carrie Redlich, M.D., M.P.H.
Professor of Medicine and Associate Director, Occupational and Environmental Medicine Program, Department of Internal Medicine, School of Medicine, Yale University
Recommended by: NIOSH