Pre-Exposure Prophylaxis (PrEP)
Pre-exposure prophylaxis (or PrEP) is a way for people who do not have HIV but who are at very high risk of getting HIV to prevent HIV infection by taking a pill every day. The pill (brand name Truvada) contains two medicines (tenofovir and emtricitabine) that are used in combination with other medicines to treat HIV. When someone is exposed to HIV through sex or injection drug use, these medicines can work to keep the virus from establishing a permanent infection.
When taken daily, PrEP is highly effective for preventing HIV. Studies have shown that PrEP reduces the risk of getting HIV from sex by about 99% when taken daily. Among people who inject drugs, PrEP reduces the risk of getting HIV by at least 74% when taken daily. PrEP is much less effective if it is not taken consistently.
As PrEP only protects against HIV, condoms are important for the protection against other STDs.
Condoms are also an important prevention strategy if PrEP is not taken consistently.
Resources for Consumers
- PrEP Basics
- Let’s Stop HIV Together Campaign: PrEP Resources
- Pocket Guide: PrEP and Folding Instructions
- Info Sheet: PrEP 101
- Flyer: Paying for PrEP
- Fact Sheet: Acute HIV Infection: Information about Acute HIV Infection and PrEP
- Fact Sheet: Truvada Medication Information Sheet for Patients
- Brochure: Now’s the Time To Find Out About PrEP
- Brochure: Taking PrEP – A Daily Pill to Reduce Your Risk of Getting HIV
- Video: Are You Ready for PrEP?
- Page last reviewed: September 26, 2019
- Page last updated: September 26, 2019
- Content source: Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention