Vaccine Schedule & Dosing
The Dengvaxia dengue vaccine requires three doses administered subcutaneously and given 6 months apart for full protection.
| Preparation | Requires mixing of diluent and lyophilized vaccine antigen in single use vials |
|---|---|
| Dosage | 0.5 mL per dose |
| Route | Subcutaneous injection |
| Schedule | Three-dose series, given 6 months apart |
Co-administration
Trials have evaluated co-administration of Dengvaxia with other vaccines, including yellow fever, diphtheria, tetanus, acellular pertussis (DTaP), inactivated polio, Haemophilus influenzae types b and a, and measles, mumps, and rubella (MMR). No safety issues have been reported.
Vaccine providers should follow best practice guidance from the Advisory Committee on Immunization Practices, which states that injectable, live-attenuated vaccines not administered simultaneously should be separated by at least 4 weeks.
Vaccine Administration After Dengue Virus Infection
Children and adolescents with dengue should wait at least 6 months after the date the dengue infection is confirmed to begin the vaccine series.