Purpose

Background
Most people in the United States are at low risk for TB. CDC's work in the United States supports a dual approach to testing and treating TB. Treatment of TB disease reduces individual morbidity and prevents transmission within communities while treatment of latent TB infection prevents TB disease.
Prompt diagnosis and treatment of TB protects individuals, families, and communities, and requires continued partnerships between public health programs, health care providers, and communities, especially in populations at increased risk for TB. Ongoing collaboration is essential to reduce TB-associated morbidity and accelerate progress towards TB elimination in the United States.
About the data
TB trends
Figure. TB cases* and rates,† by birth origin§ — United States, 2010–2025
TB case counts and rates declined for nearly three decades in the United States, with a sharp decrease in 2020, before increasing from 2021 to 2024. Compared with 2024, TB case counts and rates declined slightly among both U.S.-born and non-U.S.–born persons in 2025.
*Case counts are based on data reported to the National Tuberculosis Surveillance System as of February 12, 2026.
†Annual tuberculosis rates were calculated as cases per 100,000 persons. Rates for all U.S. cases were calculated using midyear population estimates from the U.S. Census Bureau's 2010-2020 National Intercensal Population Totals and Vintage 2025 data; rates by birth origin were calculated using midyear estimates from the Current Population Survey.
§Persons born in the United States or certain U.S. territories or elsewhere to at least one U.S. citizen parent are categorized as U.S.-born. All other persons are categorized as non-U.S.–born. Case counts for persons without a known origin of birth are not represented in the figure.
TB cases and rates
Table 1. TB cases and rates, by jurisdiction — United States, 2024 and 2025
In 2025, 10,260 TB cases were provisionally reported with a corresponding rate of 3.0 cases per 100,000 population. This represented a decrease of 1% in cases and 2% in rates from 2024 to 2025. Twenty-six states and the District of Columbia reported decreases in TB case counts and rates from 2024 to 2025.
| Jurisdiction | No. of cases* | TB rate† | ||||
|---|---|---|---|---|---|---|
| 2024 | 2025 | % change 2024 to 2025 |
2024 | 2025 | % change 2024 to 2025§ |
|
| All | 10,395 | 10,260 | -1 | 3.1 | 3.0 | -2 |
| Alabama | 90 | 89 | -1 | 1.7 | 1.7 | -2 |
| Alaska | 90 | 77 | -14 | 12.2 | 10.4 | -15 |
| Arizona | 210 | 201 | -4 | 2.8 | 2.6 | -5 |
| Arkansas | 119 | 81 | -32 | 3.8 | 2.6 | -32 |
| California | 2,109 | 2,150 | 2 | 5.4 | 5.5 | 2 |
| Colorado | 78 | 103 | 32 | 1.3 | 1.7 | 32 |
| Connecticut | 87 | 104 | 20 | 2.4 | 2.8 | 19 |
| Delaware | 24 | 19 | -21 | 2.3 | 1.8 | -22 |
| District of Columbia | 33 | 31 | -6 | 4.8 | 4.5 | -6 |
| Florida | 674 | 675 | 0 | 2.9 | 2.9 | -1 |
| Georgia | 254 | 306 | 20 | 2.3 | 2.7 | 19 |
| Hawaii | 117 | 125 | 7 | 8.2 | 8.7 | 7 |
| Idaho | 22 | 16 | -27 | 1.1 | 0.8 | -28 |
| Illinois | 352 | 384 | 9 | 2.8 | 3.0 | 9 |
| Indiana | 136 | 167 | 23 | 2.0 | 2.4 | 22 |
| Iowa | 47 | 60 | 28 | 1.5 | 1.9 | 27 |
| Kansas | 116 | 63 | -46 | 3.9 | 2.1 | -46 |
| Kentucky | 93 | 70 | -25 | 2.0 | 1.5 | -25 |
| Louisiana | 117 | 95 | -19 | 2.5 | 2.1 | -19 |
| Maine | 35 | 37 | 6 | 2.5 | 2.6 | 5 |
| Maryland | 220 | 220 | 0 | 3.5 | 3.5 | 0 |
| Massachusetts | 255 | 250 | -2 | 3.6 | 3.5 | -2 |
| Michigan | 165 | 150 | -9 | 1.6 | 1.5 | -9 |
| Minnesota | 194 | 164 | -15 | 3.3 | 2.8 | -16 |
| Mississippi | 49 | 49 | 0 | 1.7 | 1.7 | 0 |
| Missouri | 85 | 80 | -6 | 1.4 | 1.3 | -6 |
| Montana | 6 | 5 | -17 | 0.5 | 0.4 | -17 |
| Nebraska | 41 | 37 | -10 | 2.0 | 1.8 | -10 |
| Nevada | 75 | 72 | -4 | 2.3 | 2.2 | -5 |
| New Hampshire | 12 | 24 | 100 | 0.9 | 1.7 | 99 |
| New Jersey | 343 | 359 | 5 | 3.6 | 3.8 | 4 |
| New Mexico | 40 | 39 | -3 | 1.9 | 1.8 | -2 |
| New York | 1,082 | 967 | -11 | 5.4 | 4.8 | -11 |
| North Carolina | 249 | 249 | 0 | 2.3 | 2.2 | -1 |
| North Dakota | 11 | 18 | 64 | 1.4 | 2.3 | 62 |
| Ohio | 197 | 188 | -5 | 1.7 | 1.6 | -5 |
| Oklahoma | 65 | 76 | 17 | 1.6 | 1.8 | 16 |
| Oregon | 87 | 100 | 15 | 2.0 | 2.3 | 15 |
| Pennsylvania | 228 | 224 | -2 | 1.7 | 1.7 | -2 |
| Rhode Island | 23 | 19 | -17 | 2.1 | 1.7 | -18 |
| South Carolina | 83 | 97 | 17 | 1.5 | 1.7 | 15 |
| South Dakota | 12 | 13 | 8 | 1.3 | 1.4 | 7 |
| Tennessee | 164 | 141 | -14 | 2.3 | 1.9 | -15 |
| Texas | 1,288 | 1,295 | 1 | 4.1 | 4.1 | -1 |
| Utah | 51 | 35 | -31 | 1.5 | 1.0 | -32 |
| Vermont | 4 | 4 | 0 | 0.6 | 0.6 | 0 |
| Virginia | 225 | 194 | -14 | 2.6 | 2.2 | -14 |
| Washington | 257 | 264 | 3 | 3.2 | 3.3 | 2 |
| West Virginia | 8 | 9 | 13 | 0.5 | 0.5 | 13 |
| Wisconsin | 69 | 65 | -6 | 1.2 | 1.1 | -6 |
| Wyoming | 4 | 0 | -100 | 0.7 | 0.0 | -100 |
*Case counts are based on data reported to the National Tuberculosis Surveillance System as of February 12, 2026.
†Annual tuberculosis rate is calculated as cases per 100,000 persons using midyear population estimates from the U.S. Census Bureau's Vintage 2025 data.
§Percentage change in rate was calculated with unrounded numbers.
Characteristics of persons with TB
Anyone can get TB, but TB affects some groups more than others. Compared with 2024, TB rates decreased among all age groups, except among persons 65 years or older in 2025.
Consistent with previous years, in 2025, TB disease disproportionally affected non-U.S.–born persons. Among non-U.S.–born persons, there were 7,858 (77%) provisionally reported TB cases, with a corresponding rate of 15.4 per 100,000 persons. Among U.S.-born persons, there were 2,252 (22%) provisionally reported TB cases with a corresponding rate of 0.8 per 100,000 persons.
Table 2. Characteristics of persons with TB — United States, 2024 and 2025
| Characteristic | No. of cases (%)* | TB rate† | ||||||
|---|---|---|---|---|---|---|---|---|
| 2024 | 2025 | % change 2024 to 2025 |
2024 | 2025 | % change 2024 to 2025§ |
|||
| Age group,¶ yrs | ||||||||
| 0–4 | 267 | (3) | 217 | (2) | -19 | 1.4 | 1.2 | -19 |
| 5–14 | 254 | (2) | 196 | (2) | -23 | 0.6 | 0.5 | -23 |
| 15–24 | 1,143 | (11) | 1,046 | (10) | -8 | 2.6 | 2.4 | -10 |
| 25–44 | 3,504 | (34) | 3,429 | (33) | -2 | 4.0 | 3.8 | -4 |
| 45–64 | 2,676 | (26) | 2,649 | (26) | -1 | 3.3 | 3.2 | -1 |
| >65 | 2,518 | (24) | 2,632 | (26) | 5 | 4.2 | 4.3 | 1 |
| U.S.-born**,††,§§,¶¶ | 2,295 | (22) | 2,252 | (22) | -2 | 0.8 | 0.8 | -4 |
| Hispanic or Latino | 663 | (29) | 685 | (30) | 3 | 1.6 | 1.5 | -5 |
| American Indian or Alaska Native | 110 | (5) | 107 | (5) | -3 | 4.7 | 4.5 | -4 |
| Asian | 102 | (4) | 143 | (6) | 40 | 1.2 | 1.6 | 30 |
| Black or African American | 772 | (34) | 660 | (29) | -15 | 2.1 | 1.8 | -16 |
| Native Hawaiian or Other Pacific Islander | 87 | (4) | 62 | (3) | -29 | 10.3 | 8.9 | -13 |
| White | 514 | (22) | 535 | (24) | 4 | 0.3 | 0.3 | 4 |
| Multiple race | 35 | (2) | 31 | (1) | -11 | 0.5 | 0.4 | -16 |
| Other race*** | 7 | (0) | 18 | (1) | 157 | — | — | — |
| Non-U.S.–born**,††,§§,††† | 8,035 | (77) | 7,858 | (77) | -2 | 15.7 | 15.4 | -2 |
| Hispanic or Latino | 3,197 | (40) | 3,035 | (39) | -5 | 13.1 | 12.7 | -3 |
| American Indian or Alaska Native | 3 | (0) | 7 | (0) | 133 | 3.1 | 7.3 | 134 |
| Asian | 2,891 | (36) | 2,964 | (38) | 3 | 22.5 | 21.8 | -3 |
| Black or African American | 1,294 | (16) | 1,176 | (15) | -9 | 24.8 | 22.1 | -11 |
| Native Hawaiian or Other Pacific Islander | 165 | (2) | 109 | (1) | -34 | 54.4 | 44.4 | -18 |
| White | 292 | (4) | 265 | (3) | -9 | 3.6 | 3.4 | -6 |
| Multiple race | 102 | (1) | 171 | (2) | 68 | 50.4 | 80.3 | 59 |
| Other race*** | 71 | (1) | 76 | (1) | 7 | — | — | — |
*Case counts are based on data reported to the National Tuberculosis Surveillance System as of February 12, 2026.
†Annual tuberculosis rates for age group, birth origin, and race/ethnicity are calculated as cases per 100,000 persons using midyear estimates from the Current Population Survey.
§Percentage change in rate was calculated with unrounded numbers.
¶Age was missing or unknown for 33 cases in 2024 and 91 cases in 2025.
**Persons born in the United States or certain U.S. territories or elsewhere to at least one U.S. citizen parent are categorized as U.S.-born. All other persons are categorized as non-U.S.–born.
††Persons who identified as Hispanic or Latino were categorized as "Hispanic," regardless of self-reported race. Persons who did not identify as Hispanic or Latino were categorized by self-reported race; if more than one race was reported, the person was categorized as "Multiple race."
§§Birth origin was missing or unknown for 65 cases in 2024 and 150 cases in 2025.
¶¶Race or ethnicity were missing or unknown for 5 cases in 2024 and 11 cases in 2025 among U.S.-born persons.
***TB rates were not available for persons who identified as other race because population data for this group are not available from the U.S. Census Bureau.
†††Race and ethnicity were missing or unknown for 20 cases in 2024 and 55 cases in 2025 among non-U.S.–born persons.