The mpox website is being restructured to improve the quality of information. If you cannot find the information you’re looking for, please use the search bar or search for archived materials on

NewNotice: Mpox illnesses, including severe infections, continue to occur across the United States. CDC recommends people with the sexual risk factors for mpox get vaccinated now if they have not already received two doses of JYNNEOS vaccine. Those at risk include (but are not limited to) men who have sex with men (MSM) who have more than one sexual partner and those who have sex with them, regardless of gender. CDC does not currently recommend more than two vaccine doses.

Get Both Doses of the Mpox Vaccine

Vaccination is an important tool in preventing the spread of mpox. The vaccine may still protect against severe illness, hospitalization, and death. Get vaccinated with both doses of the vaccine for the best protection.

Mpox Vaccines

View print, video, and social media resources for mpox.

What’s New & Updated