Mpox Vaccine Equity Pilot Program
On September 15, 2022, the Centers for Disease Control and Prevention (CDC) launched the Mpox Vaccine Equity Pilot Program (VEPP). This program was developed to support innovative ways to reach populations most affected by mpox that were experiencing mpox vaccination disparities, such as Black/African American and Hispanic/Latino gay, bisexual, and other men who have sex with men, as well as people who are transgender. Barriers to vaccination may include language differences, inability to access vaccination sites, lack of transportation, lack of paid time off, low vaccine confidence, mistrust of government, and lack of access to online scheduling technology. Additionally, people may avoid vaccination events oriented toward specific sexual or gender identities or sexual activities out of fear of being stigmatized. State, territorial, or local health departments, tribal governments or tribal organizations, and non-governmental organizations could apply to VEPP. Jurisdictions with an approved VEPP application could receive JYNNEOS vaccine replenishment following an outreach event. Vaccines provided through VEPP were set aside to ensure more vaccines were equitably reaching communities where the outbreak was most severe and did not count towards a jurisdiction’s JYNNEOS supply threshold set by the Administration for Strategic Preparedness and Response.
On February 15, 2023, CDC stopped accepting applications for VEPP due to the wide-spread availability and supply of the JYNNEOS vaccine, and the implementation of long-term vaccine equity efforts. CDC will continue to monitor the outbreak and vaccine equity and is ready to resume VEPP, if needed. Jurisdictions with approved VEPP applications were not impacted by the VEPP application acceptance pause and could continue to work on their vaccine distribution activities.
VEPP accepted 28 applications from 14 states and Puerto Rico. Approved applications were categorized into two strategies. In the first strategy, jurisdictions implemented vaccination events designed to reach populations disproportionately affected by mpox who are also experiencing vaccination disparities, including Black/African American and Hispanic/Latino gay, bisexual, and other men who have sex with men, as well as people who are transgender. In the second strategy, jurisdictions implemented vaccination events with a broad reach, such as public festivals, general Pride events, and outreach through bars, nightclubs, and other venues frequented by members of the LGBTQIA+ community.
Background, strategies, actions, and resources to increase the number and effectiveness of prevention strategies that advance health equity among populations most affected by mpox, including vaccination efforts.
- For questions regarding obtaining vaccine supply, please contact your State, Tribal, Local, or Territorial health department.
- Please see the Immunization Program Directory for a list of immunization program directors, by state.
Learn more about some of the Vaccine Equity Pilot Program events.Response Stories
Charlotte Pride Parade participants ride past a sign offering mpox vaccine to event attendees.
The Michigan Department of Health and Human Services collaborates with local partners to bring mpox vaccination services to venues frequented by persons experiencing vaccination disparities, including this Detroit nightclub.
A mobile health unit was utilized for mpox vaccination during the 2022 Atlanta Black Pride festival
A Southern Decadence Health Hub sign advertising vaccination for mpox and COVID-19 greets visitors at the main entrance to Armstrong Park in New Orleans, Louisiana
- Mpox Toolkit for Owners and Employees of Sex-On-Premises/Commercial Sex Venues
- Mpox Toolkit for People Who Work in Sex Trades or Conduct Outreach to Sex Workers
- A Health Equity Approach for Implementation of JYNNEOS Vaccination at Large, Community-Based LGBTQIA+ Events — Georgia, August 27–September 5, 2022
- Characteristics of JYNNEOS Vaccine Recipients Before and During a Large Multiday LGBTQIA+ Festival — Louisiana, August 9–September 5, 2022
- CDC Foundation Emergency Response Fund to Support Mpox
- Mpox Community of Practice #1 Recording from 27 Oct 2022