NMI Notes

NMI Notes

Overall Updates



  • The next National Notifiable Diseases Surveillance System (NNDSS) eSHARE session is scheduled for Thursday, 4/29/2021, from 3:00 to 4:30 PM ET. Please note the date change and extended time frame.
  • The April eSHARE webinar will provide important training for current and new users of the Message Validation, Processing, and Provisioning System (MVPS) Portal.
    • At the beginning of May, MVPS will start processing data from all NNDSS case notification formats.
    • New functionality in the MVPS Portal will allow users to view message and case count information from all message formats, verify cases for low-incidence conditions, and delete cases through the user interface.
    • This webinar will be a valuable opportunity to learn how to use the new functionality and management of new user roles and permissions.
  • Access past eSHARE presentations at the NNDSS eSHARE website.

COVID-19 Vaccination Information

  • CDC encourages jurisdictions to send vaccine history information in coronavirus disease 2019 (COVID-19) case notifications using these options:
  • Full COVID-19 message mapping guide (MMG),
  • COVID Lite (generic v2 MMG plus vaccine history from COVID-19 MMG), or
  • DCIPHER/HHS Protect CSV upload using the updated January 2021 CSV template.
  • Find resources at the NNDSS Technical Resource Center.

COVID-19 Value Sets Updated

Core Requested Data Elements for COVID-19

  • As resources allow, jurisdictions are encouraged to send additional case information through the CSV upload to DCIPHER or through the COVID-19 MMG.

NNDSS 2020 Annual Data Reconciliation

  • Jurisdictions will reconcile data using MVPS.
    • Jurisdictions will view and extract the line list and aggregate tables from MVPS for all NNDSS case notification methods:
      • HL7 (including generic version 1 and varicella messages),
      • National Electronic Telecommunications System for Surveillance (NETSS), and
      • NEDSS Base System (NBS) master message.
    • Jurisdictions can work at their own pace but must still meet the established deadline.
    • The process for state epidemiologist sign-off will be in MVPS.
  • Timeline: CDC recognizes the demands of the pandemic on jurisdictions and CDC resources; to accommodate this, the timeline for reconciliation of the 2020 data is delayed compared to a non-pandemic year.
    • June 2021: Jurisdictions receive training and have access to line lists and aggregate tables in MVPS.
    • September 30, 2021: Jurisdiction deadline for sign-off on final data.

Join a Cohort to Jumpstart Your MMG Implementations!

  • The NNDSS Association of Public Health Laboratories Technical (APHL) assistance team provides technical assistance to help groups—also known as cohorts—of public health agencies build and implement NNDSS HL7 case notification messages.
  • The APHL assistance team has established cohorts of four-six public health agencies focusing on the generic v2 and the COVID-19 MMGs.
  • APHL and NBS subject matter experts guide participants through planning, gap analysis, data extraction, HL7 message creation, and validation. At completion, public health agencies will be ready to begin onboarding.
  • For those interested in joining a cohort, please email the CDC Electronic Data Exchange mailbox at edx@cdc.gov.

Production HL7 Case Notification Messages

MMGs in Production

Arboviral v1.3


Congenital Syphilis and Sexually Transmitted Diseases

Coronavirus Disease 2019

  • MMG and Data Elements
    • The MMG and artifacts are available on the NNDSS Technical Resource Center.
    • Due to the evolving nature of COVID-19 vaccines and lab testing, the value sets that are affected will be updated regularly.
      • The COVID-19 case notification vocabulary view in the PHIN Vocabulary Access and Distribution System (PHIN VADS) will be updated routinely to reflect these changes.
  • Onboarding
    • The COVID-19 MMG is open for onboarding, and the first cohort has begun onboarding. For those interested in implementing the COVID-19 MMG, please email edx@cdc.gov.

Foodborne and Diarrheal Diseases 

Generic v2

  • The MMG and artifacts are available on the NNDSS Technical Resource Center.
  • There are 33 jurisdictions in production for generic v2.
  • Guam, New Hampshire, Puerto Rico, West Virginia, and Wyoming are engaged in onboarding.

Healthcare-Associated Infections, Multi-Drug Resistant Organisms (HAI MDRO)


Lyme and Tickborne Rickettsial Diseases (TBRD)


Mumps and Pertussis

Respiratory Invasive Bacterial Disease


Tuberculosis and Latent Tuberculosis Infection


Developing HL7 Case Notification Messages

Developing HL7 Case Notification Messages

Bacterial Special Pathogens (Stage I—Draft)

  • Prioritization of response activities has delayed the external review comment period to gather jurisdiction feedback.
  • CDC expects to post the four MMGs (anthrax, brucellosis, Hansen’s disease, and leptospirosis) for external review in mid-2021.

Carbon Monoxide Poisoning (Stage II—Pilot Test-ready)

  • CDC has postponed the pilot start date.

Lead Poisoning (Requirements Analysis)

  • No new updates at this time.

Listeriosis (Stage I—Draft)

  • No new updates at this time.

Measles (Stage III—Final MMG)

Rubella and Congenital Rubella Syndrome (Stage III—Final MMG)



Jurisdiction Implementation of NNDSS HL7 Case Notification Messages

This chart shows the status of state public health departments who are piloting, receiving technical assistance, onboarding, or in production for HL7 case notification messages developed as part of the NNDSS Modernization Initiative.

Upcoming Events


NMI Notes provides monthly news updates about the National Notifiable Diseases Surveillance System (NNDSS) Modernization Initiative (NMI). It is a collaboration by the Centers for Disease Control and Prevention (CDC), Council of State and Territorial Epidemiologists (CSTE), and Association of Public Health Laboratories (APHL).

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Centers for Disease Control and Prevention | Council of State and Territorial Epidemiologists |
Association of Public Health Laboratories

Write: edx@cdc.gov        Visit: www.cdc.gov/nndss/

Ready to request technical assistance or onboarding?
Please contact edx@cdc.gov for more information.

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