EIP Network Activities

EIP activities fall into the categories of surveillance, applied research and enhanced and flexible public health practice.  Below are the activities currently conducted by the 10 EIP sites:

  • Structure and development of the Emerging Infections Program, United States Active Bacterial Core (ABCs) Surveillance, CDC and Institute of Medicine (IOM), Emerging Infections (EI) and Human Papillomavirus (HPV)image icon

    This image illustrates the elements and activities of the Emerging Infections Program (EIP).

    The Human Papillomavirus (HPV) Vaccine Impact Monitoring Project (HPV-IMPACT) is an active, population-based laboratory surveillance project for high-grade cervical lesions that could progress to invasive cervical cancer if left untreated. The goal of HPV-IMPACT is to monitor the impact of HPV vaccines on women in the United States. HPV-IMPACT was established in 2008 and includes defined areas in five states covering 1.5 million women at risk. Data from HPV-IMPACT is used to monitor the impact of the HPV vaccination program in the United States and evaluate vaccine effectiveness.

  • Prion surveillance detects or monitors the continued absence of new forms of human prion disease and provides data on the background incidence and trends of Creutzfeldt-Jakob disease (CJD), in order to inform prion disease-related public health policies.
  • Arbovirus surveillance monitors domestic and travel-associated cases of arboviral diseases, provides recommendations for arboviral specimen collection including specimen type and timing, and improved understanding in diagnosis, clinical spectrum, geographic distribution, and public health importance of emerging pathogens.
  • Rotavirus surveillance studies the vaccine intake of oral rotavirus vaccine in infants in the United States and the correlation of vaccine response based on the differing genetic factors of infants.  This information informs how vaccines can be optimized to reduce morbidity and mortality from rotavirus.
  • Congenital Cytomegalovirus (CMV) infections address the lack of a validated test to screen for CMV by establishing the clinical sensitivity of using dried blood spots (DBS), which is routinely used to screen for a variety of other birth defects.
  • TickNet is a public health network, created to foster greater collaboration between state health departments, academic centers, and the CDC on surveillance and prevention of tickborne diseases. Research activities are conducted through EIP and includes laboratory surveys, high-quality prevention trials, and pathogen discovery.

Surveillance efforts of these core EIP activities generate reliable estimates of the incidence of certain infections and provide the foundation for a variety of epidemiologic studies to explore risk factors, spectrum of disease, and prevention strategies.