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Measles Lab Manual from the World Health Organization

Manual for the Laboratory Diagnosis of Measles and Rubella Virus Infection, 2nd edition, August 2007 from the World Health Organization (WHO)

This manual provides information about the WHO Laboratory Network for Measles and Rubella including detailed protocols for cell culture, virus isolation, collection and handling of specimens for the isolation and identification of measles virus. There is also information on biosafety and international shipping regulations. These techniques have been used successfully at the Centers for Disease Control and Prevention for investigation of measles outbreaks.

The development and progress of the WHO Measles and Rubella Laboratory Network was summarized in a 2016 article in CDC’s Morbidity and Mortality Weekly Report.

The WHO Manual for the Laboratory-based Surveillance of Measles, Rubella, and Congenital Rubella Syndrome is available on the WHO web site: