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Perinatal Hepatitis B Prevention Coordinators

This page is a resource center for CDC’s funded state, local, and territorial programs that focus on preventing Hepatitis B virus transmission from pregnant women to their newborns.

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Perinatal Hepatitis B Coordinator List
Maintained by CDC’s National Center for Immunization and Respiratory Diseases

National Quality, Forum (NQF) Measure 0475 “Hepatitis B Vaccine Coverage Among All Live Newborn Infants Prior to Hospital or Birthing Facility Discharge”

The National Quality Forum (NQF) has endorsed the Centers for Disease Control and Prevention NQF Perinatal Measure 0475 “Hepatitis B Vaccine Coverage Among All Live Newborn Infants Prior to Hospital or Birthing Facility Discharge.” This measure was 1 of 14 measures formally endorsed by the NQF Board of Directors on April 2, 2012. Measure 0475 can be found on the NQF website and was updated there on April 2, 2014 with e-specification for calculation of the measure, which can also be found on the Agency for Healthcare Research and Quality’s website.

As a quality indicator, each hospital/birthing facility is encouraged to measure the rate of administration of the first dose of hepatitis B vaccine prior to discharge among all live infants born in their hospital/birthing facility during a specific time period (usually one calendar year). Hospitals are asked to exclude infants whose parents refused vaccination. Please find below documents outlining the specifications for the measure and an appendix of the ICD-9 codes and ICD-10 codes that might be used to calculate the hepatitis B birth dose coverage rate.
NQF #0475 [PDF – 3 pages]     AppendixA [PDF – 2 pages]

CDC Resources

Program Forms

Articles Generated from Perinatal Hepatitis B Prevention Program Data

Veselsky SL, Walker TY, Fenlon N, Teo C, Murphy TV. Discrepant hepatitis B surface antigen results in pregnant women screened to identify hepatitis B virus infection. Pediatrics. 2014 October; 165(4): 773-778.

Schillie S, Walker T, Veselsky S, Crowley S, Dusek C, Lazaroff J, Morris SA, Onye K, Ko S, Fenlon N, Nelson NP, Murphy TV. Outcomes of infants born to women infected with hepatitis B. Pediatrics. 2015 May;135(5):e1141-7. doi: 10.1542/peds.2014-3213. Epub 2015 Apr 20. PubMed PMID: 25896839.

Ko SC, Schillie SF, Walker T, Veselsky SL, Nelson NP, Lazaroff J, Crowley S, Dusek C, Loggins K, Onye K, Fenlon N, Murphy TV. Hepatitis B vaccine response among infants born to hepatitis B surface antigen-positive women. Vaccine. 2014 Apr 11;32(18):2127-33. doi: 10.1016/j.vaccine.2014.01.099. Epub 2014 Feb 22. PubMed PMID: 24560676.

Ko SC, Fan L, Smith EA, Fenlon N, Koneru AK, Murphy TV. Estimated Annual Perinatal Hepatitis B Virus Infections in the United States, 2000-2009. J Pediatric Infect Dis Soc. 2014 Dec 18. pii: piu115. [Epub ahead of print] PubMed PMID: 26407247.

Policies and Procedures for Prenatal Care and Delivery Hospitals

Scientific Resources/Recommendations

Hepatitis B Vaccination Recommendations for Infants, Children, and Adolescents
MMWR 2005;54(RR-16)

Appendix A: Case Finding and Management of Hepatitis B Surface Antigen (HBsAg)
Appendix B: Immunization Management Issues
Appendix C: Postexposure Prophylaxis of Persons with Discrete Identifiable Exposures to Hepatitis B Virus (HBV)

Corrected Table 4: Hepatitis B Immunization Management of Preterm Infants Weighing <2,000 g, by Maternal Hepatitis B Surface Antigen (HBsAg) Status [PDF – 1 page]

Assay Tables – 2012 updates

Sources For HBIG

HBIG page
HBIG Tables for download [PDF – 2 pages]

Program Manuals

Perinatal Hepatitis B Prevention Program Manual
Michigan Department of Community Health

Perinatal Hepatitis B Prevention Program Manual [PDF – 83 pages]
New York State Department of Health

Perinatal Hepatitis B Prevention Program Manual
Texas Department of State Health Services

Educational Materials (English & Other Languages)

CDC educational materials about hepatitis B including tools for pregnant women.

Laboratory Reporting of Pregnancy Status for Hepatitis B-positive Women

Information for laboratory reporting of HBsAg-positive pregnant women

Perinatal Hepatitis B Prevention Program Quarterly Conference Call Dates

CDC staff from Immunization Services Division and the Division of Viral Hepatitis hold quarterly calls with Perinatal Hepatitis B Prevention Program Coordinators. The calls are held from 2:00 to 3:30 PM (eastern time) on the following dates:

  • Wednesday July 12, 2017
  • Wednesday October 11, 2017

Helpful Links

Asian Liver Center

Maternal Hepatitis B Screening and Reporting Requirements (by State)

Immunization Action Coalition

Perinatal Hepatitis B Coordinators Listserv

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