About Eastern Equine Encephalitis Virus

For Everyone

Key points

  • Eastern equine encephalitis is caused by a virus spread to people through the bite of an infected mosquito.
  • It is a rare but serious disease.
  • People living in areas where eastern equine encephalitis virus circulates should protect themselves by preventing mosquito bites.
Culiseta melanura mosquito on a feather

Overview

Eastern equine encephalitis is a rare disease caused by a virus spread by infected mosquitoes. Only a few cases of eastern equine encephalitis are reported in the United States each year. Most cases occur in eastern or Gulf Coast states.

Did you know?

Although rare, eastern equine encephalitis is very serious. Approximately 30% of people who develop severe eastern equine encephalitis die, and many survivors have ongoing neurologic problems.

Symptoms

Symptoms of eastern equine encephalitis can include fever, headache, vomiting, diarrhea, seizures, behavioral changes, and drowsiness.

How it spreads

Eastern equine encephalitis virus spreads to people through the bites of infected mosquitoes. Rarely, the virus can also spread through solid organ transplantation.

Prevention

No vaccines or medicines are available to prevent eastern equine encephalitis in people. Reduce your risk of infection by preventing mosquito bites.

Testing and diagnosis

See your healthcare provider if you have symptoms after being exposed to mosquitoes in an area where eastern equine encephalitis virus spreads.

Treatment

No medicines are available to treat eastern equine encephalitis. Antibiotics are not effective against viruses, such as eastern equine encephalitis virus.

  • Rest, fluids, and over-the-counter pain medicines might relieve some symptoms.
  • For severe disease, patients often need to be hospitalized to receive supportive treatment, such as intravenous fluids, pain medicine, and nursing care.

For healthcare providers: Treatment and Prevention of Eastern Equine Encephalitis

Personal stories

Janeen’s story: Mosquitoes, ticks, and a weakened immune system

B cell-depleting therapy helped Janeen's father Steve enjoy his favorite pastimes—gardening and spending time with his family—while living with rheumatoid arthritis. The treatment also weakened his immune system and increased his risk of serious illness from viruses spread through mosquito and tick bites.

Sadly, Steve passed away shortly after being diagnosed with severe West Nile virus disease. His family shares his story and offers practical tips for protecting people with weakened immune systems.

Content Source
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
About This Page
Published: May 15, 2024
Updated: June 22, 2026

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: June 22, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.