Interim Guidance for SARS-CoV-2 Testing in Non-Healthcare Workplaces
Summary of Recent Changes
- Added description of nucleic acid amplification tests (NAATs) and antigen tests as types of viral tests to align with the Overview of Testing for SARS-CoV-2
- Added considerations on incorporating testing of asymptomatic individuals without known or suspected exposure to SARS-CoV-2 (screening testing) in select workplace settings as part of a workplace COVID-19 prevention and control plan
- Updated considerations on frequency of testing
- Workplace-based testing for SARS-CoV-2, the virus that causes COVID-19, could identify workers with SARS-CoV-2 infection, and thus help prevent or reduce further transmission. The purpose of this guidance is to provide employers with considerations for incorporating testing for SARS-CoV-2 into a workplace COVID-19 preparedness, response, and control plan in select non-healthcare workplaces.
- This guidance includes descriptions of different types of SARS-CoV-2 tests; scenarios where SARS-CoV-2 testing may be used; considerations for screening testing (testing asymptomatic workers with no known or suspected exposure to SARS-CoV-2); and use of antigen tests for serial screening testing, including in high-density critical infrastructure workplaces.
- Screening testing could be effective in helping to prevent transmission for select workplace settings.
- These interim considerations on SARS-CoV-2 testing strategies for select non-healthcare workplaces during the COVID-19 pandemic are based on what is currently known about the transmission and severity of COVID-19 and is subject to change as additional information becomes available.
Note: This document provides guidance on the appropriate use of testing and does not dictate the determination of payment decisions or insurance coverage of such testing, except as may be otherwise referenced (or prescribed) by another entity or federal or state agency.
The purpose of this document is to provide employers with strategies for consideration of incorporating testing for SARS-CoV-2, the virus that causes COVID-19, into workplace preparedness, response, and control plans in select non-healthcare workplaces. For workplaces with healthcare personnel, including those that work in nursing homes, please refer to Interim Guidance on Testing Healthcare Personnel for SARS-CoV-2 and Interim SARS-CoV-2 Testing Guidelines for Nursing Home Residents and Healthcare Personnel.
Employers are encouraged to collaborate with state, territorial, tribal and local health officials to determine whether and how to implement the following testing strategies and which one(s) would be most appropriate for their circumstances. These considerations are meant to supplement, not replace, any federal, state, local, territorial, or tribal health and safety laws, rules, and regulations with which workplaces must comply. These strategies should be carried out in a manner consistent with existing laws and regulations, including laws protecting employee privacy and confidentiality. They should also be carried out consistent with Equal Employment Opportunity Commission (EEOC) guidanceexternal icon regarding permissible testing policies and procedures. Employers paying for testing of employees should put procedures in place for rapid notification of results and establish appropriate measures based on testing results, including instructions regarding self-isolation and restrictions on workplace access.
SARS-CoV-2 testing may be incorporated as part of a comprehensive approach to reducing transmission in non-healthcare workplaces. Symptom screening, testing, and contact tracing are strategies to identify workers infected with SARS-CoV-2, the virus that causes COVID-19, so that actions can be taken to slow and stop the spread of the virus.
COVID-19 vaccine is currently available in limited doses; therefore, CDC’s Advisory Committee on Immunization Practices (ACIP) described recommendations for prioritization during the early phases of the vaccination program. As vaccine supply increases and additional priority groups receive vaccine, CDC’s priorities for SARS-CoV-2 testing will change and the guidance will be updated. For guidance on quarantine and testing of fully vaccinated people, please visit Interim Public Health Recommendations for Fully Vaccinated People.
Employees undergoing testing should receive clear information on
- the manufacturer and name of the test, the type of test, the purpose of the test, the performance specifications of the test, any limitations associated with the test, who will pay for the test, how the test will be performed, how and when they will receive test results, and;
- how to understand what the results mean, actions associated with negative or positive results, the difference between testing for workplace screening versus for medical diagnosis, who will receive the results, how the results may be used, and any consequences for declining to be tested.
Individuals tested are required to receive patient fact sheets as part of the test’s emergency use authorizationexternal icon (EUA).
According to the Americans with Disabilities Act (ADA), when employers implement any mandatory testing of employees, it must be “job related and consistent with business necessity.” In the context of the COVID-19 pandemic, the U.S. EEOCexternal icon notes that testing to determine if an employee has SARS-CoV-2 infection with an “accurate and reliable test” is permissible as a condition to enter the workplace because an employee with the virus will “pose a direct threat to the health of others.” EEOC notes that testing administered by employers that is consistent with current CDC guidance will meet the ADA’s business necessity standard. However, workplace-based testing should not be conducted without the employee’s consent. Employers who mandate workplace testing for SARS-CoV-2 infection should discuss further with employees who do not consent to testing and consider providing alternatives as feasible and appropriate such as reassignment to tasks that can be performed via telework.
The Occupational Safety and Health Administration has issued interim guidanceexternal icon for enforcing the requirements of 29 CFR Part 1904external icon with respect to the recording of occupational illnesses, specifically cases of COVID-19. Under OSHA’s recordkeeping requirements, COVID-19 is a recordable illnessexternal icon, and thus employers are responsible for recording cases of COVID-19, if the case meets certain requirements. Employers are encouraged to frequently check OSHA’s webpage at www.osha.gov/coronavirusexternal icon for updates.
Viral tests authorizedexternal icon by the Food and Drug Administration (FDA) are used to diagnose infection with SARS-CoV-2, the virus that causes COVID-19. Viral tests evaluate whether the virus is present in respiratory or other specimens. Results from these tests help public health officials identify and isolate people who are infected to minimize SARS-CoV-2 transmission. See FDA’s list of In Vitro Diagnostics Emergency Use Authorizationsexternal icon for more information about the performance of specific authorized tests.
- Nucleic acid amplification tests (NAATs), such as real-time reverse transcription-polymerase chain reaction (RT-PCR), detect viral ribonucleic acid (RNA) and indicate a current infection or a recent infection with prolonged viral RNA detection but without direct evidence for virus capable of replicating or of being transmitted to others. NAATs are high-sensitivity, high-specificity tests for diagnosing SARS-CoV-2 infection. Most NAATs need to be processed in a laboratory with variable time to results (~1–2 days), but some NAATs are point-of-care tests with results available in about 15–45 minutes.
- Antigen tests detect the presence of a specific viral antigen. Most can be processed at the point of care with results available in about 15–30 minutes. Antigen tests generally have similar specificity but are less sensitive than NAATs. Depending on the pre-test probability, antigen test results may need confirmation with a NAAT (e.g., a negative test in persons with symptoms or a positive test in persons without symptoms). Use of the Antigen Testing Algorithm pdf icon[147 KB, 1 page] is recommended to determine when confirmatory testing is needed.
Antibody (or serology) tests are used to detect previous infection with SARS-CoV-2 and can aid in the diagnosis of Multisystem Inflammatory Syndrome in Children (MIS-C) and in adults (MIS-A). CDC does not recommend using antibody testing to diagnose current infection. Depending on the time when someone was infected and the timing of the test, the test might not detect antibodies in someone with a current infection. In addition, it is not currently known whether a positive antibody test result indicates immunity against SARS-CoV-2; therefore, at this time, antibody tests should not be used to determine if an individual is immune against reinfection. Antibody testing is being used for public health surveillance and epidemiologic purposes. Because antibody tests can have different targets on the virus, specific tests might be needed to assess for antibodies originating from past infection versus those from vaccination. For more information about COVID-19 vaccines and antibody test results, refer to Interim Clinical Considerations for Use of mRNA COVID-19 Vaccines Currently Authorized in the United States.
For more information, please refer to Overview of Testing for SARS-CoV-2.
Diagnostic testing is intended to identify current infection in individuals and is performed when a person has signs or symptoms consistent with COVID-19, or when a person is asymptomatic but has recent known or suspected exposure to SARS-CoV-2.
Examples of diagnostic testing include:
- Testing people who have symptoms consistent with COVID-19 and who present to their healthcare provider
- Testing people as a result of contact tracing efforts
- Testing people who indicate that they were exposed to someone with a confirmed or suspected case of COVID-19
- Testing people who attended an event where another attendee was later confirmed to have COVID-19
Screening tests are intended to identify infected people who are asymptomatic and do not have known, suspected, or reported exposure to SARS-CoV-2. Screening helps to identify unknown cases so that measures can be taken to prevent further transmission.
Examples of screening testing include:
- Testing employees in a workplace setting
- Testing students, faculty, and staff in a school or university setting
- Testing a person before or after travel
- Testing at home for someone who does not have symptoms associated with COVID-19 and no known exposures to someone with COVID-19
When choosing which test to use, it is important to understand the purpose of the testing (e.g., diagnostic, screening), analytic performance of the test within the context of the level of community transmission, need for rapid results, and other considerations. Table 1 summarizes some characteristics of NAATs and antigen tests to consider. Most antigen tests that have received EUA from FDAexternal icon are authorized for testing symptomatic persons within the first 5, 7, 12, or 14 days of symptom onset. Given the risk of transmission of SARS-CoV-2 from asymptomatic and presymptomatic persons with SARS-CoV-2 infection, use of antigen tests in asymptomatic and presymptomatic persons can be considered. FDA has provided a list of FAQ for healthcare providers who are using diagnostic tests in screening asymptomatic individualsexternal icon, and the Centers for Medicare & Medicaid Services will temporarily exercise enforcement discretion pdf icon[40 KB, 1 Page]external icon to enable the use of antigen tests in asymptomatic individuals for the duration of the COVID-19 public health emergency under the Clinical Laboratory Improvement Amendments of 1988 (CLIA). Laboratories that perform screening or diagnostic testing for SARS-CoV-2 must have a CLIA certificate and meet regulatory requirements. Tests that have received an EUA from FDA for point of care (POC) use can be performed with a CLIA certificate of waiver.
Table 1. NAAT and Antigen Test Differences to Consider When Planning for Diagnostic or Screening Use
Detect current infection
Detect current infection
Viral Ribonucleic Acid (RNA)
Nasal, Nasopharyngeal, Oropharyngeal, Sputum, Saliva
Varies by test, but generally high for laboratory-based tests and moderate-high for point-of-care (POC) tests
Varies depending on the course of infection, but generally moderate-to-high at times of peak viral load*
Varies by Test
Relatively Easy to Use
Authorized for Use at the Point-of-Care
Most are not, some are
Most are, some are not
Most 1-3 days. Some could be rapid in 15 minutes
Ranges from 15 minutes to 30 minutes
Most sensitive test method available
Short turnaround time for NAAT POC tests, but few available
Usually does not need to be repeated to confirm results
Short turnaround time (approximately 15 minutes)+
When performed at or near POC, allows for rapid identification of infected people, thus preventing further virus transmission in the community, workplace, etc.
Comparable performance to NAATs in symptomatic persons and/or if culturable virus present, when the person is presumed to be infectious
Longer turnaround time for lab-based tests (1–3 days)
Higher cost per test
A positive NAAT diagnostic test should not be repeated within 90 days, because people may continue to have detectable RNA after risk of transmission has passed
May need confirmatory testing
Less sensitive (more false negative results) compared to NAATs, especially among asymptomatic people
**The decreased sensitivity of antigen tests might be offset if the POC antigen tests are repeated more frequently (i.e., serial testing at least weekly).
^ Costs for: NAATsexternal icon, Antibody testsexternal icon
+Refers to point-of-care antigen tests only.
Employers may consider conducting daily in-person or virtual health checks (e.g., symptom and temperature screening) to identify employees with signs or symptoms consistent with COVID-19 before they enter a facility, in accordance with CDC’s Guidance for Businesses and Employers Responding to Coronavirus Disease 2019 (COVID-19). Employers should follow guidance from the EEOCexternal icon regarding confidentiality of medical records from health checks.
Vaccinated and unvaccinated workers with COVID-19 symptoms should be immediately separated from other employees, customers, and visitors, and sent home or to a healthcare facility, depending on how severe their symptoms are, and follow CDC guidance for caring for oneself. To prevent stigma and discrimination in the workplace, make employee health screenings as private as possible. CDC recommends that anyone with signs or symptoms of COVID-19 be tested and follow the advice of their healthcare provider. Waiting for test results prior to returning to work is recommended to keep potentially infected workers out of the workplace.
Employers are encouraged to implement flexible sick leave and supportive policies and practices as part of a comprehensive approach to prevent and reduce transmission among employees.
Positive test results using a viral test (NAAT or antigen) in persons with signs or symptoms consistent with COVID-19 indicate that the person has COVID-19. A negative antigen test in persons with signs or symptoms of COVID-19 should be confirmed by a laboratory-based NAAT, a more sensitive test. Results from NAATs are considered the definitive result when there is a discrepancy between the antigen and NAAT test. For more information, see the Antigen Test Algorithm pdf icon[458 KB, 1 Page]. Positive test results should be interpreted to indicate that a person has COVID-19 and should not come to work and should isolate at home. Decisions to discontinue isolation for workers with COVID-19 and allow them to return to the workplace may follow either a symptom-based, time-based, or a test-based strategy (see Testing to determine resolution of infection below).
Case investigation is typically initiated when a health department receives a report from a laboratory or testing site of a positive SARS-CoV-2 viral test result, or a report from a healthcare provider of a patient with a confirmed or probable diagnosis of COVID-19pdf iconexternal icon.
In general, fully vaccinated workers with no COVID-like symptoms do not need to quarantine or be tested following an exposure to someone with suspected or confirmed COVID-19. However, those who work in congregate settings or other high-density workplaces (e.g., meat and poultry processing and manufacturing plants) should be tested after an exposure; however, they do not need to quarantine. For more guidance on quarantine and testing of fully vaccinated people, please visit Interim Public Health Recommendations for Fully Vaccinated People.
Viral testing is recommended for all unvaccinated close contacts (people who have been within 6 feet for a combined total of 15 minutes or more during a 24-hour period) of persons with COVID-19. Because of the potential for asymptomatic and pre-symptomatic transmission of SARS-CoV-2, it is important that unvaccinated individuals exposed to people with known or suspected COVID-19 be quickly identified and quarantined. Viral testing with NAATs or antigen tests can detect if these individuals are currently infected. The health department may ask the employer for assistance in identifying close contacts of the worker. Employers are encouraged to work with public health departments investigating cases of COVID-19 and tracing contacts to help reduce the spread of SARS-CoV-2 in their workplaces and communities.
Because there may be a delay between the time a person is exposed to the virus and the time that virus can be detected by testing, early testing after exposure at a single time point may miss many infections. Testing that is repeated at different points in time, also referred to as serial testing, is more likely to detect infection among close contacts of a COVID-19 case than testing done at a single point in time. Viral testing is recommended for close contacts of persons with COVID-19 who should be tested immediately after being identified, and if negative, tested again in 5–7 days after last exposure or immediately if symptoms develop during quarantine.
While CDC continues to recommend a 14-day quarantine for unvaccinated individuals who are close contacts of a person with COVID-19, viral testing may also be used as part of an option to shorten the quarantine period. Local public health authorities determine and establish the quarantine options for their jurisdictions. Shortening quarantine may increase willingness to adhere to public health recommendations. However, shortened quarantines may be less effective in preventing transmission of COVID-19 than the currently recommended 14-day quarantine. In jurisdictions with shortened quarantine options, workplaces with higher risk of SARS-CoV-2 introduction or transmission, or with potential for greater negative impact if employees become infected SARS-CoV-2 (see Types of workplaces below), can consider restricting workers from entering the workplace until 14 days after their exposure.
Testing may also be considered for unvaccinated persons who might have been in close contact with persons diagnosed with COVID-19 in collaboration with the local health department if resources permit. A risk-based approach to testing possible contacts of a person with confirmed COVID-19 may be applied. Such an approach should take into consideration the likelihood of exposure, which is affected by the characteristics of the workplace and the results of contact investigations. In some settings, expanded screening testing (i.e., testing beyond individually identified close contacts to those who are possible close contacts), such as targeting workers who worked in the same area and during the same shift, may be considered as part of a strategy to control the transmission of SARS-CoV-2 in the workplace. High-risk settings that have demonstrated potential for rapid and widespread dissemination of SARS-CoV-2 include:
- High-density critical infrastructure workplaces, where workers are in the workplace for long periods (e.g., for 8–12 hours per shift) and have prolonged close contact with coworkers
- Workplaces where employees live in congregate settingsexternal icon (e.g., fishing vessels, offshore oil platforms, farmworker housing, or wildland firefighter camps)
- Workplaces with populations at risk for severe illness if they are infected, such as homeless shelters and workplaces with older workers
After a case of COVID-19 has been identified in a high-density critical infrastructure workplace, where workers are in prolonged close contact, NAAT or antigen testing can be used to diagnose infection in workers with known or suspected exposure to SARS-CoV-2. Employers are encouraged to consult with state, local, territorial, and tribal health departments to help inform decision-making about expanded screening testing.
If employees are tested after close contact or suspected close contact with someone who has a confirmed or probable diagnosis of COVID-19, care should be taken to inform these employees of their possible exposure to SARS-CoV-2 in the workplace while maintaining confidentiality of the individual with COVID-19, as required by the ADAexternal icon and consistent with EEOC guidance regarding What You Should Know About COVID-19 and the ADA, the Rehabilitation Act, and Other EEO Lawsexternal icon.
The decision to end isolation and return to the workplace for employees with suspected or confirmed SARS-CoV-2 infection should be made in the context of clinical and local circumstances. NAATs have detected SARS-CoV-2 RNA in some recovered people’s respiratory specimens for up to 3 months after illness onset but without direct evidence that virus that can replicate or cause disease. Consequently, evidence supports a time-based and symptom-based strategy to determine when to discontinue isolation or other precautions rather than a test-based strategy. For persons who are severely immunocompromised, a test-based strategy could be considered in consultation with infectious disease experts. For all others, a test-based strategy is no longer recommended except to discontinue isolation or precautions earlier than would occur under the symptom-based strategy.
Under the ADA, employers are permitted to require a healthcare provider’s noteexternal icon to verify that employees are healthy and able to return to work. However, as a practical matter, employers should be aware that healthcare provider offices and medical facilities may be extremely busy during periods when community COVID-19 indicators are in the moderate to high categorizations (Table 2) and may not be able to provide such documentation in a timely manner. In such cases, employers should consider not requiring a healthcare provider’s note for employees who are sick to validate their illness, qualify for sick leave, or to return to work. Most people with COVID-19 have mild illness, can recover at home without medical care, and can follow CDC recommendations to determine when to discontinue isolation and return to the workplace.
Testing asymptomatic persons without known or suspected exposure to SARS-CoV-2 for early identification, isolation, and disease prevention
When to consider screening testing
Screening testing of asymptomatic workers without known or suspected exposure to SARS-CoV-2 in select non-healthcare settings may be useful to detect COVID-19 early and stop transmission quickly, particularly in areas with community COVID-19 indicators in the moderate to high categorizations (Table 2, Table 3). Screening testing can be used in addition to symptom and temperature checks, which will miss asymptomatic or presymptomatic contagious workers. Persons with asymptomatic or presymptomatic SARS-CoV-2 infection are significant contributors to SARS-CoV-2 transmission.
In general, fully vaccinated workers should continue to follow employer guidance on screening testing. Please see Interim Public Health Recommendations for Fully Vaccinated People for more information.
Workplace settings for which screening testing of workers should be considered include:
- Workplaces at increased risk of introduction of SARS-CoV-2 (e.g., workplaces where workers are in close contact with the public, such as restaurants or salons, or workplaces in communities with moderate to high transmission)
- Workplaces where there is a higher risk of SARS-CoV-2 transmission (e.g., workplaces where physical distancing is difficult and workers might be in close contact, such as manufacturing or food processing plants, or workplaces that provide congregate housing for employees such as fishing vessels, offshore oil platforms, farmworker housing or wildland firefighter camps)
- Workplaces where SARS-CoV-2 infection among employees will lead to greater negative impact, such as
Approaches may include initial testing of all workers before entering a workplace, periodic testing of workers at regular intervals, targeted testing of new workers or those returning from a prolonged absence (such as medical leave or furlough), or some combination of approaches. Given the incubation period for COVID-19 (up to 14 days), CDC recommends conducting screening testing at least weekly. Employers may find the following factors helpful to consider when determining the interval for periodic testing:
- The availability of testing, turnaround time, and cost
- The latency time period between exposure and development of a positive SARS-CoV-2 viral test
- Type of workplaces
- Level of community transmission (Table 2, Table 3)
- How many employees tested positive during previous rounds of testing
- Relevant experience with outbreaks at the workplace
Serial testing used in a screening program could identify workers with SARS-CoV-2 infection, and thus help prevent or reduce further transmission, which is an occupational health measure of great importance in the types of workplaces mentioned above. Outbreak prevention and control is increasingly being thought to depend largely on the frequency of testing and the speed of reporting (an advantage of antigen tests) and is only marginally improved by the higher test sensitivity of NAATs. Serial testing, if implemented, should be integrated as a component of the comprehensive workplace program and not a substitute for other measures, such as COVID-19 vaccination, social distancing, mask wearing, hand hygiene, and cleaning and disinfection. Engineering controls and improved ventilation in settings such as office buildings and schools are also important.
For screening testing, some antigen test results should be considered presumptive (preliminary results). A positive antigen screening test result should be considered presumptive when the pretest probability (likelihood that the person being tested actually has the infection) for COVID-19 is low or moderate for the purpose of making a clinical diagnosis (e.g., a worker who is asymptomatic and has no known exposures to COVID-19). Asymptomatic employees who have a positive antigen screening test result should undergo a confirmatory NAAT. They should not come to work and should quarantine during confirmatory testing.
According to test manufacturers, negative antigen tests results are presumptive for the purpose of making a clinical diagnosis. A negative antigen screening test result does not need to be followed by confirmatory testing if the pretest probability is low or serial antigen testing will be performed.
NAATs do not need to be routinely repeated for confirmation. Employees with a positive NAAT result should not come to work and should isolate at home. A negative NAAT result is interpreted as no evidence of SARS-CoV-2 infection at the time when the testing sample was collected. Employees who test negative should continue to take steps to protect themselves and others.
State, local, territorial, and tribal health departments may be able to provide assistance on any local context or guidance impacting the workplace. Before testing a large proportion of asymptomatic workers without known or suspected exposure, employers are encouraged to have a plan in place for how they will ensure access to clinical evaluation and confirmatory testing when needed, ensure test results are reported to public health departments, modify operations based on test results, collaborate with public health departments in workplace case investigation and contact tracing, and manage a higher risk of false positive results in a low prevalence population.
|Indicator||Low Transmission||Moderate Transmission||Substantial Transmission||High Transmission|
|Cumulative number of new cases per 100,000 persons within the last 7 days*||<10||10-49||50-99||≥100|
|Percentage of NAATs that are positive during the last 7 days†||<5%||5%-7.9%||8%-9.9%||≥10.0%|
Indicators should be calculated for counties or core based statistical areas, although in rural areas with low population density, multiple jurisdictions might need to be combined to make the indicators more useful for decision-making. The indicators listed can be found by county on CDC’s COVID Data Tracker Website under “county view”.
@ If the two indicators suggest different transmission levels, the higher level should be selected.
* Number of new cases in the county (or other administrative level) in the last 7 days divided by the population in the county (or other administrative level) and multiplying by 100,000.
† Number of positive tests in the county (or other administrative level) during the last 7 days divided by the total number of tests resulted in the county (or other administrative level) during the last 7 days. Calculating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Laboratory Test Percent Positivity: CDC Methods and Considerations for Comparisons and Interpretation.
Table 3. Potential Actions based on Community Indicator Level
|Facilitate diagnostic testing for symptomatic persons and all close contacts of cases|
|Facilitate diagnostic testing for symptomatic persons and all close contacts of cases|
|Implement screening testing of select groups at least weekly plus facilitate diagnostic testing of symptomatic persons and close contacts|
|Implement screening testing of select groups at least weekly plus facilitate diagnostic testing of symptomatic persons and close contacts|
- Chin ET, Huynh BQ, Chapman LAC, Murrill M, Bash S, Lo NC. Frequency of routine testing for Coronavirus Disease 2019 (COVID-19) in high-risk healthcare environments to reduce outbreaks. Clin Infect Dis: 26 October 2020. https://doi.org/10.1093/cid/ciaa1383external icon
- Denny TN, Andrews L, Bonsignori M, Cavanaugh K, Datto MB, Deckard A, DeMarco CT, DeNaeyer N, Epling CA, Gurley T, Haase SB, Hallberg C, Harer J, Kneifel CL, Lee MJ, Louzao R, Moody MA, Moore Z, Polage CR, Puglin J, Spotts PH, Vaughn JA, Wolfe CR. Implementation of a pooled surveillance testing program for asymptomatic SARS-CoV-2 infections on a college campus — Duke University, Durham, North Carolina, August 2–October 11, 2020. MMWR Morb Mortal Wkly Rep 2020;69(46):1743–1747. https://doi.org/10.15585/mmwr.mm6946e1external icon
- Grassley NC, Pons-Salort M, Parker EPK, White PJ, Feruson NM; Imperial College COVID-19 Response Team. Comparison of molecular testing strategies for COVID-19 control: a mathematical modelling study. Lancet Infect Dis 2020; 20(12):1381–1389. https://doi.org/10.1016/S1473-3099(20)30630-7external icon
- Kucirka LM, Lauer LA, Laeyendecker O, Boon D, Lessler J. Variation in false-negative rate of reverse transcriptase polymerase chain reaction–based SARS-COV-2 tests by time since exposure. Ann Int Med 2020;173(4):262–267. https://doi.org/10.7326/M20-1495external icon
- Larremore DB, Wilder B, Lester E, Shehata S, Burke JM, Hey JA, Tambe M, Mina MJ, Parker R. Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening. Sci Adv 2021;7(1):eabd5393. https://doi.org/10.1126/sciadv.abd5393external icon
Revisions made on October 21, 2020
- Added links to the updated close contact definition.
- Updated language to align with updated definition.