National Botulism Surveillance Summary, 2018
In 2018, health departments reported 242 cases of botulism to CDC. Of those, 231 were laboratory-confirmed and 11 were probable. The cases were of the following types: 162 (67%) infant, 61 (25%) wound, 18 (7%) foodborne, and 1 (<1%) other, diagnosed as probable adult intestinal colonization.
Infant botulism cases
Health departments reported 162 cases infant botulism, all of which were laboratory-confirmed (Table 1). Cases were reported from 31 states, with California (38 cases, 23%) and Pennsylvania (27, 17%) reporting the most. The toxin types were A (69, 43%), B (87, 54%), Ba (2, 1%), Bf (3, 2%), and F (1, <1%). Type Bf infant botulism is very uncommon; previously, only 13 U.S. cases had been reported (7 from California, 5 from Texas, 1 from New Mexico).
The median age of infants was 4 (range: 0–10) months; 89 (55%) were female. One death was reported. Three infants had used pacifiers containing honey purchased in Mexico. 
Wound botulism cases
Health departments reported 61 cases of wound botulism, 51 laboratory-confirmed and 10 probable.
The 51 cases of laboratory-confirmed wound botulism were reported from four states: 44 from California, 5 from Arizona, and 1 each from New Mexico and Oregon (Table 1). All cases occurred in persons who injected drugs. Most (47, 92%) were toxin type A and the remainder (4, 8%) were toxin type B. Six cases were part of outbreaks among persons who injected black tar heroin:
- California reported an outbreak of 3 cases in San Diego County within a 2-week period in April 2018 among persons who shared needles. 
- Arizona reported an outbreak of 3 cases in Gila County in a married couple and their friend within a 9-day period in June–July 2018. The three people involved shared black tar heroin.
The median age of patients with laboratory-confirmed wound botulism was 48 (range: 21–67) years; 36 (71%) were male. One death was reported. This year marks the highest annual case count of laboratory-confirmed wound botulism. The next highest years were 1999 (40 cases) and 2006 (45 cases).
The 10 cases of probable wound botulism were reported from 3 states: 8 from California, 1 from Arizona and 1 from Texas. All cases occurred in persons who injected drugs. The median age of patients was 46 (range: 24–62) years; five (50%) were men. No deaths were reported.
Foodborne botulism cases
Health departments reported 18 cases of foodborne botulism, 17 laboratory-confirmed and one probable.
- New York reported a type A outbreak of 3 cases linked to home-canned peas and beans. 
- Pennsylvania reported a type B outbreak of 2 cases linked to homemade fermented bean curd.
- New Jersey reported a type E outbreak of 2 cases linked to home-prepared feseekh, a fermented salt-cured fish. 
- Oklahoma reported a type F outbreak of 2 cases linked to homemade turkey soup.
The 4 cases in Alaska were caused by toxin type E; they were linked to Native Alaskan foods served at unrelated events. Texas reported a type A case without an identified food source, but unsafe food practices were observed. The median age of patients with laboratory-confirmed botulism was 55 (range: 20–88) years; 13 (76%) were female. No deaths were reported.
The one case of probable foodborne botulism was reported from Alaska. The patient had recently eaten seal oil. The patient did not die.
Other cases of botulism
One case of laboratory-confirmed botulism caused by toxin type F reported from Texas was thought to be due to adult intestinal colonization. No risk factors were identified.
|Transmission Category||Cases||Median Age
|Infant||162||4 (0–10) months||1||male 73 (45); female 89 (55)||A: 69 (43), B: 87 (54), Ba: 2 (1), Bf: 3 (2), F: 1 (<1)||0|
|Wound||51||48 (21–67) years||1||male 36 (71); female 15 (29)||A: 47 (92), B: 4 (8)||2|
|Foodborne||17||55 (20–88) years||0||male 4 (24); female 13 (76)||A: 6 (35), B: 3 (18), E: 6 (35), F: 2 (12)||4|
|Other‡||1||30 (30–30) years||0||male 1 (100)||F: 1 (100)||0|
|Transmission Category||Cases||Median Age
n (%) type
|Wound¶||10||46 (24–62) years||0||male 5 (50); female 5 (50)||not applicable||0|
|Foodborne§||1||59 (59–59) years||0||male 1 (100)||not applicable||0|
*Outbreak defined as two or more cases resulting from a common exposure.
†IDU: injection drug use.
‡“Other” includes adult intestinal colonization, iatrogenic botulism, and unknown routes of transmission.
¶Probable wound botulism is defined as a clinically compatible case with no suspected exposure to contaminated food and with a history in the 2 weeks before illness began of either a fresh contaminated wound or injection drug use.
§Probable foodborne botulism is defined as a clinically compatible case with an epidemiologic link (e.g., ingestion of a home-canned food within the previous 48 hours).
|Month||State||Activity Associated with Infection||Vehicle||Toxin Type||Cases|
|April||California||Injection drug use||Shared needles||A||3|
|June – July||Arizona||Injection drug use||Shared black tar heroin||A||3|
Figure 1. Botulism Cases by State or Territory and Transmission Category—United States, 2018
Figure 2. Laboratory-confirmed botulism cases by state/territory and toxin type—United States, 2017
- Food and Drug Administration, FDA Reminds Parents Not to Feed Honey to Children Younger Than 1 Year. 2018.
- Peak, C.M., et al., Wound Botulism Outbreak Among Persons Who Use Black Tar Heroin – San Diego County, California, 2017-2018. MMWR Morb Mortal Wkly Rep, 2019. 67(5152): p. 1415-1418.
- Bergeron, G., et al., Notes from the Field: Botulism Outbreak Associated with Home-Canned Peas – New York City, 2018. MMWR Morb Mortal Wkly Rep, 2019. 68(10): p. 251-252.
- Ganapathiraju PV, Gharpure R, Thomas D, et al. Notes from the Field: Botulism Type E After Consumption of Salt-Cured Fish — New Jersey, 2018. MMWR Morb Mortal Wkly Rep. 2019; 68: p. 1008–1009. DOI: http://dx.doi.org/10.15585/mmwr.mm6844a3external icon
Centers for Disease Control and Prevention (CDC). Botulism Annual Summary, 2018. Atlanta, Georgia: U.S. Department of Health and Human Services, CDC, 2021.