In 1992, the US Congress passed the Fertility Clinic Success Rate and Certification Act. This law requires the Centers for Disease Control and Prevention (CDC) to publish pregnancy success rates for assisted reproductive technology (ART) fertility clinics in the United States. More details about the law are available online at CDC’s Fertility Clinic Success Rate and Certification Act website.

Since 1995, CDC has worked in consultation with the Society for Assisted Reproductive Technology and the American Society for Reproductive Medicine to report ART success rates. This report is based on the latest available data on the type, number, and outcome of ART cycles performed in US clinics.

The 2021 Assisted Reproductive Technology Fertility Clinic and National Summary Report has four major sections:

Commonly Asked Questions About the US National ART Surveillance System

This section provides background information on infertility and ART; an explanation of the data collection, analysis, and publication processes; and links to resources for people experiencing infertility or people interested in ART.

How to Access and Interpret Fertility Clinic Success Rates

This section provides information on how to access and interpret fertility clinic success rates, which are available online for each reporting fertility clinic in the United States.

National ART Summary

This section presents ART results and success rates from data combined from all US clinics. It provides this information in a summary table and in figures that use ART data from all reporting clinics to answer specific questions related to ART use and outcomes.


Appendix A: Data Validation
This section provides information about this year’s data validation activities.

Appendix B: Glossary of Terms
This section provides definitions for technical and medical terms used throughout the report.

Appendix C: ART Clinics
This section includes the names and addresses of all reporting fertility clinics, along with a list of clinics known to be in operation in 2021 that did not report their data to CDC as required by law.

This report is intended for the general public, and the emphasis is on presenting the information in an easily understandable format. CDC hopes that this report is informative and helpful to people considering an ART procedure. Please contact us with any questions or suggestions at