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Dimethylformamide

Synonyms & Trade Names
Dimethyl formamide, N,N-Dimethylformamide, DMF
CAS No.
68-12-2
RTECS No.
DOT ID & Guide
2265 129
Formula
HCON(CH₃)₂
Conversion
1 ppm = 2.99 mg/m3
IDLH
500 ppm
See: 68122
Exposure Limits
NIOSH REL
TWA 10 ppm (30 mg/m3) [skin]
OSHA PEL
TWA 10 ppm (30 mg/m3) [skin]
Measurement Methods
NIOSH 2004;
OSHA 66
See: NMAM or OSHA Methods
Physical Description
Colorless to pale-yellow liquid with a faint, amine-like odor.
Molecular Weight
73.1
Boiling Point
307°F
Freezing Point
-78°F
Solubility
Miscible
Vapor Pressure
3 mmHg
Ionization Potential
9.12 eV
Specific Gravity
0.95
Flash Point
136°F
Upper Explosive Limit
15.2%
Lower Explosive Limit
(212°F): 2.2%
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
Incompatibilities & Reactivities
Carbon tetrachloride; other halogenated compounds when in contact with iron; strong oxidizers; alkyl aluminums; inorganic nitrates
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin, respiratory system; nausea, vomiting, colic; liver damage, enlarged liver; high blood pressure; face flush; dermatitis; In Animals: kidney, heart damage
Target Organs
Eyes, skin, respiratory system, liver, kidneys, cardiovascular system
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated
Remove:When wet or contaminated
Change:No recommendation
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Water flush promptly
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

NIOSH

Up to 100 ppm:
(APF = 10) Any supplied-air respirator*

Up to 250 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode*

Up to 500 ppm:
(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode*
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 0457   MEDICAL TESTS: 0091
Page last reviewed: October 30, 2019