Drug Overdoses
Data are for the U.S.
Mortality
- Number of drug overdose deaths: 106,699
- Drug overdose deaths per 100,000 population: 32.1
Source: National Vital Statistics System – Mortality Data (2021) via CDC WONDER
- Drug overdose deaths involving any opioid per 100,000 population: 24.2
Source: National Vital Statistics System – Mortality Data (2021) via CDC WONDER
- Drug overdose deaths involving synthetic opioids other than methadone per 100,000 population: 21.3
Source: National Vital Statistics System – Mortality Data (2021) via CDC WONDER
- Drug overdose deaths involving heroin per 100,000 population: 2.8
Source: National Vital Statistics System – Mortality Data (2021) via CDC WONDER
- Drug overdose deaths involving natural and semisynthetic opioids per 100,000 population: 4.1
Source: National Vital Statistics System – Mortality Data (2021) via CDC WONDER
Related FastStats
- All Injuries
- Accidents/Unintentional Injuries
- Illicit Drug Use
- Suicide/Self-Inflicted Injury
- Therapeutic Drug Use
More data: reports and tables
- Trends in Drug Overdose from Health, United States
- Health, United States — Topic Page: Drug overdose deaths
- NCHS Fact Sheet – NCHS Data on Drug Overdose Deaths
- Estimates of Drug Overdose Deaths Involving Fentanyl, Methamphetamine, Cocaine, Heroin, and Oxycodone: United States, 2021 [PDF – 499 KB]
- Drug Overdose Deaths Involving Xylazine: United States, 2018–2021 [PDF – 661 KB]
- Co-Involvement of Opioids in Drug Overdose Deaths involving Cocaine and Psychostimulants, 2011-2021
- Drug Overdose Deaths in the United States, 2001–2021
- Drug Overdose Mortality by Usual Occupation and Industry: 46 U.S. States and New York City, 2020 [PDF – 656 KB]
- Urban–Rural Differences in Drug Overdose Death Rates, 2020
- Drug Overdose Deaths in Adults Ages 65 and Over: United States, 2000–2020
- MMWR Opioid reports
More data: query tools
- Provisional Drug Overdose Death Counts
- NCHS Data Visualization on Drug Poisoning Mortality 1999-2016
- CDC WONDER – Multiple Cause-of-Death Data
- CDC WONDER – Underlying Cause of Death
- Web-based Injury Statistics Query and Reporting System (WISQARS)
- Drug Use-Associated Hospital Encounters Data From Selected Hospitals