Leading Causes of Death

Data are for the U.S.

Number of deaths for leading causes of death
  • Heart disease: 695,547
  • Cancer: 605,213
  • COVID-19: 416,893
  • Accidents (unintentional injuries): 224,935
  • Stroke (cerebrovascular diseases): 162,890
  • Chronic lower respiratory diseases: 142,342
  • Alzheimer’s disease: 119,399
  • Diabetes: 103,294
  • Chronic liver disease and cirrhosis : 56,585
  • Nephritis, nephrotic syndrome, and nephrosis: 54,358

Source: Mortality in the United States, 2021, data table for figure 4

Note: Final data for 2021. Provisional data for 2022 and 2023 are available through CDC Wonder