Table 1. Recommended Adult Immunization Schedule for ages 19 years or older, United States, 2021

Always make recommendations by determining needed vaccines based on age (Table 1), assessing for medical conditions and other indications (Table 2), and reviewing special situations (Notes).

COVID-19 Vaccination

ACIP recommends use of COVID-19 vaccines for everyone ages 12 and older within the scope of the Emergency Use Authorization for the particular vaccine. COVID-19 vaccine and other vaccines may be administered on the same day. See the COVID-19 Vaccine Product Information page for additional information about COVID-19 vaccines authorized for use in the United States.

Legend

Recommended vaccination for adults who meet age requirement, lack documentation of vaccination, or lack evidence of past infection

Recommended vaccination for adults with an additional risk factor or another indication

Recommended vaccination based on shared clinical decision-making

No recommendation/Not applicable

adult vaccine schedule
Vaccine 19-26 years 27-49 years 50-64 years ≥65 years
Influenza inactivated (IIV) or
Influenza recombinant (RIV4) more info icon.
1 dose annually
more info icon.
Influenza live attenuated
(LAIV4) more info icon.
more info icon.
1 dose annually
Tetanus, diphtheria, pertussis
(Tdap or Td) more info icon.
1 dose Tdap each pregnancy; 1 dose Td/Tdap for wound management (see notes)
1 dose Tdap, then Td or Tdap booster every 10 years
Measles, mumps, rubella
(MMR) more info icon.
1 or 2 doses depending on indication (if born in 1957 or later)
Varicella
(VAR) more info icon.
2 doses (if born in 1980 or later) 2 doses
Zoster recombinant
(RZV) more info icon.
2 doses
Human papillomavirus
(HPV) more info icon.
2 or 3 doses depending on age at initial vaccination or condition 27 through 45 years
Pneumococcal conjugate
(PCV13) more info icon.
1 dose
1 dose
Pneumococcal polysaccharide
(PPSV23) more info icon.
1 or 2 doses depending on indication 1 dose
Hepatitis A
(HepA) more info icon.
2 or 3 doses depending on vaccine
Hepatitis B
(HepB) more info icon.
2 or 3 doses depending on vaccine
Meningococcal A, C, W, Y
(MenACWY) more info icon.
1 or 2 doses depending on indication, see notes for booster recommendations
Meningococcal B
(MenB) more info icon.
2 or 3 doses depending on vaccine and indication, see notes for booster recommendations
19 through 23 years
Haemophilus influenzae type b
(Hib) more info icon.
1 or 3 doses depending on indication

Administer recommended vaccines if vaccination history is incomplete or unknown. Do not restart or add doses to vaccine series if there are extended intervals between doses. The use of trade names is for identification purposes only and does not imply endorsement by the ACIP or CDC.

Notes

Recommended Adult Immunization Schedule for ages 19 years or older, United States, 2021

For vaccine recommendations for persons 18 years of age or younger, see the Recommended Child/ Adolescent Immunization Schedule.

Additional information

COVID-19 Vaccination

ACIP recommends use of COVID-19 vaccines for everyone ages 12 and older within the scope of the Emergency Use Authorization for the particular vaccine. COVID-19 vaccine and other vaccines may be administered on the same day. See the COVID-19 Vaccine Product Information page for additional information about COVID-19 vaccines authorized for use in the United States.

Haemophilus influenzae type b vaccination

Special situations

Hepatitis A vaccination

Routine vaccination

Special situations

Hepatitis B vaccination

Routine vaccination

Special situations

Human papillomavirus vaccination

Routine vaccination

Shared clinical decision-making

Special situations

Influenza vaccination

Routine vaccination

Special situations

Measles, mumps, and rubella vaccination

Routine vaccination

Special situations

Meningococcal vaccination

Special situations for MenACWY

Shared clinical decision-making for MenB

Special situations for MenB

Pneumococcal vaccination

Routine vaccination

Shared clinical decision-making

Special situations

(https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6140a4.htm)

Tetanus, diphtheria, and pertussis vaccination

Routine vaccination

Special situations

Varicella vaccination

Routine vaccination

Special situations

Zoster vaccination

Routine vaccination

Special situations

 

Vaccines in the Adult Immunization Schedule

adult vaccine schedule
Vaccines Abbreviations Trade names
Haemophilus influenzae type b Hib ActHIB®
Hiberix®
PedvaxHIB®
Hepatitis A vaccine HepA Havrix®
Vaqta®
Hepatitis A and hepatitis B vaccine HepA-HepB Twinrix®
Hepatitis B vaccine HepB Engerix-B®
Recombivax HB®
Heplisav-B®
Human papillomavirus vaccine HPV vaccine Gardasil 9®
Influenza vaccine, inactivated IIV  Many brands
Influenza vaccine, live, attenuated LAIV4 FluMist® Quadrivalent
Influenza vaccine, recombinant RIV4 Flublok Quadrivalent®
Measles, mumps, and rubella vaccine MMR M-M-R® II
Meningococcal serogroups A, C, W, Y vaccine MenACWY-D
MenACWY-CRM
MenACWY-TT
Menactra®
Menveo®
MenQuadfi®
Meningococcal serogroup B vaccine MenB-4C
MenB-FHbp
Bexsero®
Trumenba®
Pneumococcal 13-valent conjugate vaccine PCV13  Prevnar 13®
Pneumococcal 23-valent polysaccharide vaccine PPSV23  Pneumovax® 23
Tetanus and diphtheria toxoids Td Tenivac®
Tdvax™
Tetanus and diphtheria toxoids and acellular pertussis vaccine Tdap Adacel®
Boostrix®
Varicella vaccine VAR  Varivax®
Zoster vaccine, recombinant RZV  Shingrix

This schedule is recommended by the Advisory Committee on Immunization Practices (ACIP) and approved by the Centers for Disease Control and Prevention (CDC), American College of Physicians (ACPexternal icon), American Academy of Family Physicians (AAFPexternal icon), American College of Obstetricians and Gynecologists (ACOGexternal icon), American College of Nurse-Midwives (ACNMexternal icon), and American Academy of Physician Assistants (AAPAexternal icon).

The comprehensive summary of the ACIP recommended changes made to the adult immunization schedule can be found in the February 12, 2021 MMWR.


Report

Injury Claims
All vaccines included in the adult immunization schedule except pneumococcal 23-valent polysaccharide (PPSV23) and zoster (RZV) vaccines are covered by the Vaccine Injury Compensation Program. Information on how to file a vaccine injury claim is available at www.hrsa.gov/vaccinecompensationexternal icon.

Questions or comments
Contact www.cdc.gov/cdc-info or 800-CDC-INFO (800-232-4636), in English or Spanish, 8 a.m.–8 p.m. ET, Monday through Friday, excluding holidays.

Helpful information


Page last reviewed: February 12, 2021