Vaccine 2D Barcode Scanning for Vendors

Since the Implementation Pilot for 2D Vaccine Barcode Utilization in 2011, many electronic health information system vendors have incorporated 2D barcode scanning capability into their systems. This page has information for vendors and system developers interested in adding the capability of data processing data from 2D barcodes on vaccine products and Vaccine Information Statements (VIS) into their systems. This includes those involved in the design, development, and implementation of electronic medical records (EMRs), electronic health records (EHRs), practice management software (PMS), and Immunization Information Systems (IISs).

Updated Guidance for Documenting Vaccine NDCs and Lot Numbers in IISs and EHRs – June 2017

This document pdf icon[3 pages] provides guidance for capturing National Drug Codes (NDCs) and lot number information for administered vaccines in EHRs or IISs.

Software Functional Capabilities Guide

The EMR/IIS 2D Barcode Functional Capabilities Guide pdf icon[47 pages] documents the EMR/IIS functional capabilities needed to process 2D barcodes on vaccine products and VIS documents. This report can be used as a guide to design and develop systems with 2D barcode processing capabilities. The July 2013 initial publication of this report was updated in September 2016, May 2017, October 2018, December 2019, and September 2020 to enhance the Guide with additional lessons learned. A Change Log is included on page 3.

Vaccine NDC Crosswalk Tables

To aid the ability to realize 2D barcode scanning functionality in electronic health information systems, CDC has developed vaccine National Drug Code (NDC) crosswalk tables. The purpose of the vaccine NDC crosswalk tables is to show the relationships of vaccine primary and secondary packaging NDCs and to provide related information. The NDC on vaccine primary packaging differs from the NDC on the vaccine secondary packaging. The NDC crosswalk tables contain the Global Trade Identification Number (GTIN) for vaccines with a 2D barcode applied. NDCs are embedded within the GTINs. The application of 2D barcodes onto vaccine primary packaging is an ongoing effort. As applications of 2D barcodes increase, the NDC crosswalk tables will be updated. Additionally, the crosswalk tables will be maintained regularly to reflect new and retired NDCs. The crosswalk tables are available on the CDC IIS Code Set web-page.


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Page last reviewed: January 19, 2021