2019 State and City TB Report

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Completion of Therapy

Fully treating and, therefore, preventing further spread of M. tuberculosis is key to TB control and elimination. If TB drugs are stopped too soon or not taken correctly, a person may develop symptoms again or drug resistance may develop, enabling the further spread of TB. Each patient is unique. There are many reasons why a patient might be unable or unwilling to complete TB treatment, such as:

  • No longer experiencing symptoms of TB, not fully understanding the treatment regimen
  • Not being willing or able to manage side effects of their treatment regimen
  • Cultural beliefs
  • Language barriers
  • Difficulty getting health care
  • Substance use
  • Mental health issues

Completion of therapy among persons who have experienced homelessness or been incarcerated can be particularly challenging due to difficulty locating patients for follow-up care and treatment, but is particularly important because of the risk of transmission at shelters or in the jail or prison systems.

2019 State and City Report

Figure 9. Percentage of Newly Diagnosed TB Cases Completing Treatment ≤12 Months, United States, 2017

There are several ways to increase treatment completion. These include:

  • Directly observed therapy (i.e., patients are observed to ingest each dose of anti-TB medications)
  • Use of incentives and enablers (e.g., gift cards for food or bus fare for transportation to get to and from the health department) to get patients to complete treatment

TB treatment is complex and can take several months to complete.  It can take up to 2 years to have full treatment information reported for each TB patient.  As a result, the most recent information available on completion of therapy is from patients in the 50 states and 9 cities who were identified with TB in 2017.

For these patients, 20 states and one city met or exceeded the 2025 national target of 95.0% of TB cases completing a full treatment regimen in 12 months or less; 14 states and 2 cities were short of the 2025 target but met or exceeded the national average (89.8%) (Figure 9).

Additionally, in 2017 there were 7 states and 5 cities that reported more than 7 TB patients, ’15 years of age who experienced homelessness in the year prior to diagnosis; 7 of these 12 jurisdictions exceeded the national average of 80.7% completion of therapy among homeless TB patients (Table 1).

There were 8 states and 2 cities in 2017 that reported more than 4 TB patients, 15 years of age or older who were incarcerated at TB diagnosis; 6 of these 10 jurisdictions exceeded the national average of 73.1% completion of therapy among incarcerated TB patients (Table 2 ).

Table 1. Treatment Completion within 12 Months or Less among Newly Diagnosed TB Patients Age ≥15 who Experienced Homelessness within the Year Prior to Diagnosis, United States, 2017

States with 1 to 3 TB patients age ≥ 15 who were homeless
States* with 1 to 3 TB patients age >15  experiencing homelessness Percentage of patients age >15 experiencing homelessness who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months
Connecticut 100.0 98.0
New Hampshire 100.0 88.2
Pennsylvania 100.0 86.0
Wisconsin 100.0 90.0
Illinois 100.0 91.6
Michigan 100.0 96.0
Kansas 100.0 100.0
Maryland 100.0 82.6
Nevada 100.0 98.5
New Jersey 100.0 92.9
Louisiana 66.7 82.4
Philadelphia 66.7 60.3
Alaska 50.0 91.5
Missouri 50.0 73.6
States with 4 to 7 TB patients age ≥ 15 who were homeless
States* with 4 to 7 TB patients age >15 experiencing homelessness Percentage of  patients age >15 experiencing homelessness who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months
Arkansas 100.0 78.9
Colorado 100.0 91.2
Indiana 100.0 96.4
Oregon 100.0 90.2
Ohio 100.0 82.3
Virginia 100.0 97.2
Minnesota 100.0 95.7
Mississippi 100.0 86.4
Washington 100.0 93.4
North Carolina 85.7 93.6
Alabama 80.0 87.9
New York 80.0 92.6
Hawaii 75.0 96.9
San Francisco 75.0 88.5
District of Columbia 42.9 76.7
South Carolina 40.0 92.0
States with 8 or more TB patients age ≥ 15 who were homeless
States* with 8 or more TB patients age >15 experiencing homelessness Percentage of  patients age >15 experiencing homelessness who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months
Massachusetts 100.0 94.6
Chicago 100.0 90.6
Houston 92.3 85.8
Tennessee 91.7 95.2
Arizona 84.6 92.5
Florida 82.1 95.2
New York City 81.8 92.9
California 77.5 89.3
Los Angeles 74.1 92.1
San Diego 64.7 89.6
Georgia 61.5 86.3
Texas 60.0 82.0
Texas 68.0 84.0

Table 2. Treatment Completion within 12 Months or Less among Newly Diagnosed TB Patients Age ≥15 who were Incarcerated at the Time of Diagnosis, United States, 2017

States with 1 to 2 TB patients age > 15 who were incarcerated
States with 1 to 2 TB patients age ≥ 15 who were incarcerated Percentage of incarcerated patients age ≥ 15 who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months†
Alaska 100.0 91.5
Connecticut 100.0 98.0
District of Columbia 100.0 76.7
Indiana 100.0 96.4
New Jersey 100.0 92.9
New York 100.0 92.6
Oklahoma 100.0 95.8
West Virginia 100.0 84.6
Arkansas 100.0 78.9
Delaware 100.0 100.0
Mississippi 100.0 86.4
New Mexico 100.0 96.0
Minnesota 50.0 95.7
South Carolina 50.0 92.0
Virginia 50.0 97.2
Illinois 0.0 91.6
Philadelphia 0.0 60.3
States with 3 to 4 TB patients age > 15 who were incarcerated
States with 3 to 4 TB patients age ≥ 15 who were incarcerated Percentage of incarcerated patients age ≥ 15 who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months†
Los Angeles 100.0 92.1
Massachusetts 100.0 94.6
North Carolina 100.0 93.6
Alabama 100.0 87.9
New York City 100.0 92.9
Colorado 66.7 91.2
Louisiana 66.7 82.4
Georgia 60.0 89.3
States with 5 or more TB patients age ≥ 15 who were incarcerated
States with 5 or more TB patients age ≥ 15 who were incarcerated Percentage of homeless patients age ≥ 15 who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months†
Tennessee 100.0 95.2
Washington 100.0 93.4
Arizona 94.4 92.5
Houston 85.7 85.8
Florida 83.3 95.2
San Diego 80.0 89.6
Georgia 71.4 86.3
Missouri 66.7 73.6
California 63.6 89.3
Texas 46.8 82.0
Footnotes

Figure 9.  Percentage of Newly Diagnosed TB Cases Completing Treatment ≤12 Months, United States, 2017

The fraction in each parenthesis reports the number of TB patients who completed treatment within 12 months out of the total number of patients who were eligible to complete treatment within 12 months.

States/cities are grouped into thirds based on numbers of TB cases reported in 2017.

Baltimore, DC, DE, IA, ID, KS, ME, MT, ND, NE, NH, NM, RI, SD, UT, VT, WV, WI and WY reported 50 or fewer total TB cases in 2017. Due to the small denominator, data should be interpreted with caution.

Data source: National Tuberculosis Surveillance System as of June 10, 2020

Table 1. Treatment Completion within 12 Months among Newly Diagnosed TB Patients Age ≥15  who Experienced Homelessness within the Year Prior to Diagnosis, United States, 2017

*States/cities are grouped into thirds based on numbers of homeless TB cases reported in 2017.

^Among those age >15 who were eligible to complete treatment within 12 months

Among all patients of any age who were eligible to complete treatment within 12 months

Note: Baltimore, DE, IA, ID, KY, ME, MT, NE, ND, NM, OK, RI, SD, UT, VT, WV, WY did not report TB cases among persons age ≥15 experiencing homelessness who were eligible to complete treatment.

Data source: National Tuberculosis Surveillance System as of June 10, 2020

Table 2. Treatment Completion within 12 Months or Less among Newly Diagnosed TB Patients Age ≥15 who were Incarcerated at the Time of Diagnosis, United States, 2017

*States/cities are grouped into thirds based on numbers of incarcerated TB cases reported in 2017.

^Among those age ≥15 who were eligible to complete treatment within 12 months

Among all patients of any age who were eligible to complete treatment within 12 months

Note: Baltimore, Chicago, HI, IA, ID, KS, KY, MD, ME, MI, MT, ND, NE, NH, NV, OH, OR, PA, RI, San Francisco, SD, UT, VT, WI, WY did not report TB cases among incarcerated persons age ≥15 who were eligible to complete treatment.

Data source: National Tuberculosis Surveillance System as of June 10, 2020