Syphilis can have very serious consequences when left untreated.

Syphilis can have very serious complications when left untreated.

hand and tablet computer

You should get tested regularly if you are pregnant, are a man who has sex with men, have HIV infection, and/or have partner(s) who have tested positive for syphilis.

two men holding hands

The majority of reported male primary and secondary (P&S) syphilis cases where sex of sex partner is known are among men who have sex with men (MSM).

pregnant woman and her husband talking to doctor

Syphilis is easy to cure in its early stages. Pregnant women should be tested regularly for syphilis because infection with syphilis can cause serious problems in a baby.


2021 STI Treatment Guidelines – Syphilis – Updated diagnostic, treatment, and screening recommendations for STIs (July 22, 2021)

STI Prevalence, Incidence, and Cost Estimates in the United States – 1 in 5 people in the United States had an STI on any given day in 2018. These updated estimates provide the clearest picture to date of how common and costly STIs are in the United States. (January 25, 2021)

The State of STDs in the United States – This *customizable* infographic highlights statistics for chlamydia, gonorrhea, and syphilis, as well as the populations most affected by these STDs, consequences when left untreated, and ways to prevent them. (April 13, 2021)

Syphilis Success Stories
Success Story
The Alaska Division of Public Health, CDC, and community members worked together to get to the bottom of a syphilis outbreak in Anchorage.
Success Story
Nine CDC-funded jurisdictions made great strides in establishing and activating systems to help identify and prevent congenital syphilis in their communities.
Success Story
The Louisiana Department of Health’s STD/HIV Program is pulling out all of the stops to tackle increases in syphilis and its impact on women and babies in the state.
badge icon
See More Success Stories