Photos and Videos of Naegleria fowleri

A wet mount of Naegleria fowleri trophozoites cultured from the cerebrospinal fluid (CSF) of a patient with primary amebic meningoencephalitis (PAM) viewed using phase contrast microscopy. Magnification: 600x.

A cytospin of fixed CSF showing a Naegleria fowleri trophozoite (arrow) stained with Giemsa-Wright amidst polymorphonuclear leukocytes and a few lymphocytes. Within the trophozoite, the nucleus and nucleolus can be seen. Magnification: 1000x.

A section of the cerebral portion of the brain from a PAM patient, stained with hematoxylin and eosin, showing large clusters of Naegleria fowleri trophozoites and the destruction of the normal brain tissue architecture. Cysts are not seen. Magnification: 100x. Inset: Higher magnification (1000x) of Naegleria fowleri trophozoites (arrows) with the characteristic nuclear morphology.

A section of the cerebral portion of the brain from a PAM patient reacted with the specific anti-Naegleria fowleri antibody which has been conjugated to a fluorescent antibody (immunofluorescent staining) viewed using microscopy with an exciter filter. Note the large numbers of Naegleria fowleri trophozoites staining bright green. No cysts are seen. Magnification: 100x.

A section of the brain from a PAM patient stained with hemotoxylin and eosin showing a large cluster of Naegleria fowleri trophozoites surrounding capillaries. Magnification: 400x.

Extensive hemorrhage and necrosis are present in the brain, mainly in the frontal cortex.

Extensive hemorrhage and necrosis are present in the brain, mainly in the frontal cortex.

Focal hemorrhage and necrosis in frontal cortex due to Naegleria fowleri.

Focal hemorrhage and necrosis in frontal cortex due to Naegleria fowleri.