Release
Provisional data from CDC's National Center for Health Statistics indicate there were an estimated 69,973 drug overdose deaths in the United States during 2025—a decrease of almost 14% from the 81,313 deaths estimated in 2024.
Almost all states across the nation saw decreases; Rhode Island, New York, North Carolina, Alabama and Vermont experienced declines of 25% or more. In contrast, New Mexico, Arizona and Colorado had increases of 10% or more compared to the same period in 2024.
The new data show that overdose deaths involving opioids decreased from an estimated 55,296 in 2024 to 44,564 in 2025. Overdose deaths involving cocaine and psychostimulants (like methamphetamine) decreased as well.
The data will be featured in an interactive web data visualization that will be updated Wednesday, May 13. The 2025 data presented in this visualization are provisional—they are incomplete and subject to change as more 2025 data are submitted to the National Vital Statistics System.
The visualization includes:
- Reported and predicted (estimated) provisional counts of deaths due to drug overdose occurring nationally and in each jurisdiction.
- U.S. map of the percentage changes in provisional drug overdose deaths for the 12-month period ending in December 2025 compared with the 12-month period ending in December 2024, by jurisdiction.
- Reported and predicted provisional counts of drug overdose deaths involving specific drugs or drug classes occurring nationally and in selected jurisdictions.
- The latest update includes provisional drug overdose death statistics for Puerto Rico. These figures are not reflected in the overall U.S. total.
NCHS releases both reported and predicted provisional drug overdose death counts each month. They represent the numbers of these deaths due to drug overdose occurring in the 12-month periods ending in the month indicated. Deaths are reported by the jurisdiction in which the death occurred.