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Guidelines and Recommendations

Guidelines are statements that include recommendations developed using a systematic process based on prevailing guideline development standards. The Division of HIV/AIDS Prevention (DHAP) within the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) has been at the forefront in developing guidelines on HIV prevention and care with significant national and international impact on public health care practice.

New Publications and/or Updates

HIV Testing

Technical Update on HIV-1/2 Differentiation Assays
This is a technical update to the 2014 CDC guideline Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations (2014), in response to changes in the commercial availability of HIV-1/HIV-2 antibody differentiation assays approved by the U.S. Food and Drug Administration (FDA) for diagnostic use.

August 2016


Updated guidelines for antiretroviral postexposure prophylaxis after sexual, injection drug use, or other nonoccupational exposure to HIV—United States, 2016
This guidelines update and expand the 2005 U.S. Department of Health and Human Services recommendations for clinical care providers regarding nonoccupational postexposure prophylaxis (nPEP) for exposure to human immunodeficiency virus (HIV) outside the health care setting for persons in the United States. The update includes pediatric dosing information.

April 18, 2016

Forthcoming Guidelines

Guidelines currently undergoing peer review: This site provides information on the independent peer review of documents defined by DHAP as influential in terms of their potential impact on public policy or the private sector. These documents include some forthcoming guideline documents.