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Guidelines and Recommendations

Guidelines are statements that include recommendations developed using a systematic process based on prevailing guideline development standards. The Division of HIV/AIDS Prevention (DHAP) within the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) has been at the forefront in developing guidelines on HIV prevention and care with significant national and international impact on public health care practice.

New Publications and/or Updates

HIV Testing

Recommendations for HIV Screening of Gay, Bisexual, and Other Men Who Have Sex with Men — United States, 2017
This MMWR policy note provides an update on CDC’s initiative to assess the benefits and harms associated with more frequent screening of MSM.

August, 2017

Technical Update Laboratory Algorithm for HIV Diagnosis
This is a technical update to the CDC guideline Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations (2014). This technical update provides information on the use of the Alere Determine HIV 1/2 Ag/Ab Combo single use rapid test (Determine) in laboratories where it is not feasible to conduct an instrumented antigen/antibody test as the initial test in the algorithm

October, 2017

Update (May 23, 2018)

Interim Statement Regarding Potential Fetal Harm from Exposure to Dolutegravir – Implications for HIV Post-exposure Prophylaxis (PEP). Please see attached PDF.


Updated guidelines for antiretroviral postexposure prophylaxis after sexual, injection drug use, or other nonoccupational exposure to HIV—United States, 2016
This guidelines updates and expands the 2005 U.S. Department of Health and Human Services recommendations for clinical care providers regarding nonoccupational postexposure prophylaxis (nPEP) for exposure to human immunodeficiency virus (HIV) outside the health care setting for persons in the United States. The update includes pediatric dosing information.

April 18, 2016

Forthcoming Guidelines

Guidelines currently undergoing peer review: This site provides information on the independent peer review of documents defined by DHAP as influential in terms of their potential impact on public policy or the private sector. These documents include some forthcoming guideline documents.

Additional CDC Guidance Documents