Notice of Funding Opportunity PS24-0047: High-Impact HIV Prevention and Surveillance Programs for Health Departments

Executive Summary

CDC announces the availability of fiscal year 2024 funds for a cooperative agreement for health departments to implement high-impact HIV prevention and surveillance programs. The purpose of this notice of funding opportunity (NOFO) is to implement a comprehensive HIV prevention and surveillance program to prevent new HIV infections and improve the health of peoples with HIV. The NOFO aligns with CDC’s Division of HIV Prevention (DHP) strategic focus areas to bolster community engagement, health equity, syndemic and whole-person approaches to HIV prevention.

Please access the NOFO by searching “CDC-RFA-PS-24-0047” to complete your application package using

Eligibility Information

The funding opportunity is for eligible health departments for core prevention and surveillance funding. Approximately 32 additional awards for eligible health departments representing the 57 jurisdictions (48 counties, District of Columbia (DC), San Juan, PR, and 7 states) included in the Ending the HIV Epidemic in the US initiative.

Attachments and Information Resources

Below is the list of Program Guidance and/or related links referenced in the NOFO.

High Impact Prevention (HIP)

HIV Testing

Partner Services

PrEP Guidance

HIV Planning Group (HPG) – Plans and Processes

Epidemiologic Profile Guidance

Social Determinants of Health

Syringe Services Program (SSP)

Cluster Detection and Response

Community Engagement

Perinatal HIV Prevention Program Guidance

Prevention with Positives (PwP) Guidelines

Data-to-Care (D2C)

Laboratory Testing Guidance

Data Security and Confidentiality Guidance

Content Review Guidelines

HIV Surveillance

Letter of Intent

CDC strongly urges you to complete a LOI prior to the submission of your application. The purpose of this letter is to inform CDC of your interest in applying for funding under PS24-0047. Although a LOI is not required and non-binding, it is highly recommended as it allows CDC program staff to estimate the number of and plan for the review of submitted applications.

Completed LOI must be electronically submitted to

An email acknowledging CDC’s receipt of a LOI submission will be sent to the potential applicant.

After you Apply

Application Submission

The application must include complete, stand-alone sections (e.g. project abstract, narrative, budget and budget justification) for each requested funding program (core and demonstration project) so that each request for a funding program can be identified and provided to the respective review panel. Each detailed budget and narrative justification should support the activities for the first year of funding in response to this NOFO and a summary narrative for the entire project period.

Application Review Information

Applications will be reviewed for completeness. Incomplete applications and applications that are non-responsive to the eligibility criteria will not advance through the review process. Applicants will be notified if the application did not meet submission requirements. All eligible and technically acceptable applications will be funded for the core HIV program. For demonstration projects, all applications deemed eligible and technically acceptable by the review panel will be funded in order of score and rank, availability of funds, geographic diversity, and relevance to DHAP program priorities.

Notice of Award (NoA)

Successful applicants will receive a Notice of Award (NoA) from the CDC Office of Grants Services (OGS). The NoA shall be the only binding, authorizing document between the recipient and CDC. The NoA will be signed by an authorized Grants Management Officer and emailed to the principle investigator (PI) and a hard copy mailed to the recipient fiscal officer identified in the application.

Any application awarded in response to this NOFO will be subject to the DUNS, CCR Registration and Transparency Act requirements.


For programmatic technical assistance, contact:
Erica K. Dunbar, Senior Advisor for Program
Department of Health and Human Services
Centers for Disease Control and Prevention
1600 Clifton Road, NE
Atlanta, GA 30333

For financial, awards management, or budget assistance, contact:
Edna Green, Grants Management Specialist
Department of Health and Human Services
Office of Grants Services
Atlanta, GA 30341

For assistance with submission difficulties related to, contact the Contact Center by phone at 1-800-518-4726. Hours of Operation: 24 hours a day, 7 days a week, except on federal holidays.

For all other submission questions, contact:
Technical Information Management Section
Department of Health and Human Services
CDC Office of Financial Resources
Office of Grants Services
2920 Brandywine Road, MS E-14
Atlanta, GA 30341
Telephone: 770-488-2700

CDC Telecommunications for persons with hearing loss is available at: TTY 1-888-232-6348.