Why CDC is Working to Prevent Global Tetanus
Updated March 31, 2022
- Maternal and neonatal tetanus remains a major public health problem globally. There is an 80%–100% case-fatality rate among infants, especially in areas with poor immunization coverage and limited access to clean deliveries and umbilical cord care.
- In 2019, the Global Burden of Disease studyexternal iconexternal icon estimated over 73,000 total tetanus cases including over 27,000 neonatal tetanus infections. An estimated 34,700 tetanus deaths occurred worldwide, most in South Asia and Sub-Saharan Africa.
- The World Health Organization reportspdf iconexternal iconpdf iconexternal icon an increasing burden of tetanus is occurring among adult men, especially in countries that do not provide tetanus booster doses. Sub-Saharan Africa has the highest number of non-neonatal tetanus cases per million population and 71% of hospitalized tetanus patients are men.
Monetary Costs: Tetanus Costs Families and Countries Millions Annually but is Inexpensive to Prevent
- In unvaccinated persons, tetanus infection almost always requires admission to the hospital for treatment. People can be hospitalized for several weeks for treatment leading to high healthcare costs. Studies on the cost of treating tetanus are limited, but a 2017 case study in the United States showed the health care cost to treat one child was over $800,000.
- Compared to the high monetary costs for treatment, preventing tetanus is a cost-effective, lifesaving intervention. The cost of delivery for one tetanus vaccine dose is estimated at less than $1 in developing countries.
- Eliminating maternal and neonatal tetanus in the remaining countries would prevent an estimatedexternal icon 70,000 neonatal tetanus deaths over a 10-year period through vaccination.
Ongoing Challenge: Many Children and Pregnant Women are Missing Out on the Benefit of Tetanus Vaccination
- Worldwide, 79 million women and their babies remain unprotected against tetanus, leaving them at risk of maternal and neonatal tetanus infection, death, or serious health complications that can be lifelong.
- An estimated 30 million children missed completing their three primary doses of tetanus containing vaccine (DTP3) during January to December 2020external icon.
- Several countries still do not provide the tetanus booster shots needed to protect people throughout life.
CDC works with partners and countries to eliminate maternal and neonatal tetanus and promote protection against tetanus throughout life.