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NPCR and SEER Incidence – U.S. Cancer Statistics Public Use Databases

U.S. Cancer Statistics: The Official Federal Cancer Statistics. National Program of Cancer Registries and SEER

Researchers can access and analyze high-quality population-based cancer incidence data on the entire United States population. De-identified cancer incidence data reported to CDC’s National Program for Cancer Registries (NPCR) and the National Cancer Institute’s (NCI’s) Surveillance, Epidemiology, and End Results (SEER) Program are available to researchers for free in public use databases that can be accessed using software developed by NCI’s SEER Program.

Cancer surveillance data from these two programs are combined to become United States Cancer Statistics (USCS), the official source for federal cancer data. Combined data from NPCR and the SEER Program include cancer incidence and population data for all 50 states, the District of Columbia, and Puerto Rico, providing information on more than 24 million cancer cases.

The databases include data by demographic characteristics (for example, age, sex, and race) and tumor characteristics (for example, year of diagnosis, site, histology, stage, and behavior). Hospitals, physicians, and laboratories across the nation report these data to central cancer registries supported by CDC and NCI. The NPCR and SEER Incidence – U.S. Cancer Statistics Public Use Databases are intended for researchers to conduct focused analyses beyond what is available through the U.S. Cancer Statistics Data Visualizations tool. Researchers can use these data to inform scientific inquiries, programs, and policies by identifying disparities in cancer burden, investigating trends and geographic distributions in cancer incidence, and evaluating and monitoring cancer prevention activities.

Two public use databases are available—

  • 2001–2015 database, which includes data for 50 states and the District of Columbia.
  • 2005–2015 database, which includes data for 50 states, the District of Columbia, and Puerto Rico.

Number of Records in the NPCR and SEER Incidence – U.S. Cancer Statistics Public Use Databases

The table below shows the number of cases available for the most recent NPCR and SEER Incidence – U.S. Cancer Statistics data release*.
Database All Cases** Malignant Cases† Malignant and In Situ Cases†
2001–2015 database (November 2017 submission) 24,697,337 22,411,632 24,108,828
2005–2015 database (November 2017 submission) 18,949,028 17,061,057 18,393,757

* The following criteria apply to the NPCR and SEER Incidence – U.S. Cancer Statistics Public Use Databases:

  • NPCR- and SEER-supported cancer registries report all incident cases coded as in situ (non-malignant) and invasive (malignant; primary site only) according to the International Classification of Diseases for Oncology, Third Edition (ICD-O-3), with the following exceptions:
    • In situ cancers of the cervix are not reported.
    • Basal and squamous cell carcinomas of the skin are not reported, except when these occur on the skin of the genital organs.
    • Non-malignant (including borderline and in situ) central nervous system tumors are reported.
    • Additionally, in situ urinary bladder cancers were re-coded as invasive behavior.
  • Cancers that were identified only through death certificate or autopsy reports and cancers in patients with unknown age or sex have been excluded from the public use databases.

**The “All Cases” column includes benign and borderline brain and central nervous system (CNS) tumors and cases coded as “no longer reportable in ICD-O-3” and “only malignant in 2010+”. See SEER Behavior Recode for Analysis for more information.

†Malignant and in situ cases are defined using the SEER Behavior Recode for Analysis.

How to Obtain Access to the Data

The data are provided and analyzed through SEER*Stat software, which is distributed by the NCI’s SEER Program.

  1. If you do not have a current SEER*Stat account, please complete a new request.
  2. Complete and sign the NPCR and SEER Incidence – U.S. Cancer Statistics Research Data Agreement. [PDF-39KB]
  3. E-mail the form to uscsdata@imsweb.com. Your request for access will be processed within 2 business days and you will receive a response notifying you when you have access to the databases in the SEER*Stat software.
  4. Download and install SEER’s SEER*Stat software. The site also provides training tutorials.
  5. A new NPCR and SEER Incidence – U.S. Cancer Statistics Research Data Agreement is required for each data submission year. You will receive notification reminding you to complete a data agreement when new data becomes available.

Supporting Documentation

Archived Documentation

Suggested Citations

The database should be cited in all publications and presentations and include the submission and release dates.

Suggested Citation for the 2001–2015 Database

National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database: NPCR and SEER Incidence – U.S. Cancer Statistics 2001–2015 Public Use Research Database, United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Released June 2018, based on the November 2017 submission. Accessed at www.cdc.gov/cancer/npcr/public-use.

Suggested Citation for the 2005–2015 Database

National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database: NPCR and SEER Incidence – U.S. Cancer Statistics 2005–2015 Public Use Research Database, United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Released June 2018, based on the November 2017 submission. Accessed at www.cdc.gov/cancer/npcr/public-use.

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