Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Enter search terms separated by spaces.

Epichlorohydrin

Synonyms & Trade Names
1-Chloro-2,3-epoxypropane; 2-Chloropropylene oxide; gamma-Chloropropylene oxide
CAS No.
106-89-8
RTECS No.
TX4900000
DOT ID & Guide
2023 131P
Formula
C3H5OCl
Conversion
1 ppm = 3.78 mg/m3
IDLH
Ca [75 ppm]
See: 106898
Exposure Limits
NIOSH REL
: Ca See Appendix A
OSHA PEL
†: TWA 5 ppm (19 mg/m3) [skin]
Measurement Methods

NIOSH 1010;
OSHA 7
See: NMAM or OSHA Methods
Physical Description
Colorless liquid with a slightly irritating, chloroform-like odor.
MW:
92.5
BP:
242°F
FRZ:
-54°F
Sol:
7%
VP:
13 mmHg
IP:
10.60 eV
Sp.Gr:
1.18
Fl.P:
93°F
UEL:
21.0%
LEL:
3.8%
Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
Incompatibilities & Reactivities
Strong oxidizers, strong acids, certain salts, caustics, zinc, aluminum, water [Note: May polymerize in presence of strong acids and bases, particularly when hot.]
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin with deep pain; nausea, vomiting; abdominal pain; resp distress, cough; cyanosis; reproductive effects; [potential occupational carcinogen]
Target Organs
Eyes, skin, respiratory system, kidneys, liver, reproductive system
Cancer Site
[in animals: nasal cancer]
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH

At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor and acid gas canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION   See ICSC CARD: 0043   See MEDICAL TESTS: 0093
 

Order NIOSH Publications

Contact Us:
USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO