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Epichlorohydrin

Synonyms & Trade Names
1-Chloro-2,3-epoxypropane, 2-Chloropropylene oxide, ã-Chloropropylene oxide
CAS No.
106-89-8
RTECS No.
TX4900000
DOT ID & Guide
2023 131P
Formula
C3H5OCl
Conversion
1 ppm = 3.78 mg/m3
IDLH
Ca [75 ppm]
See: 106898
Exposure Limits
NIOSH REL
Ca See Appendix A
OSHA PEL
TWA 5 ppm (19 mg/m3) [skin] See Appendix G
Measurement Methods
NIOSH 1010;
OSHA 7
See: NMAM or OSHA Methods
Physical Description
Colorless liquid with a slightly irritating, chloroform-like odor.
Molecular Weight
92.5
Boiling Point
242°F
Freezing Point
-54°F
Solubility
7%
Vapor Pressure
13 mmHg
Ionization Potential
10.60 eV
Specific Gravity
1.18
Flash Point
93°F
Upper Exposive Limit
21.0%
Lower Explosive Limit
3.8%
Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
Incompatibilities & Reactivities
Strong oxidizers, strong acids, certain salts, caustics, zinc, aluminum, water [Note: May polymerize in presence of strong acids and bases, particularly when hot.]
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin with deep pain; nausea, vomiting; abdominal pain; resp distress, cough; cyanosis; reproductive effects; [potential occupational carcinogen]
Target Organs
Eyes, skin, respiratory system, kidneys, liver, reproductive system
Cancer Site
[in animals: nasal cancer]
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated
Remove:When wet (flammable)
Change:No recommendation
Provide:Eyewash, Quick drench
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Soap wash immediately
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

NIOSH

At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor and acid gas canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 0043   MEDICAL TESTS: 0093
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