2020 State and City TB Report

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Completion of Therapy

Fully treating and, therefore, preventing further spread of M. tuberculosis is key to TB control and elimination. If TB drugs are stopped too soon or not taken correctly, a person may develop symptoms again or drug resistance may develop, enabling the further spread of TB. Each patient is unique. There are many reasons why a patient might be unable or unwilling to complete TB treatment, such as:

  • No longer experiencing symptoms of TB, not fully understanding the treatment regimen
  • Not being willing or able to manage side effects of their treatment regimen
  • Cultural beliefs
  • Language barriers
  • Difficulty getting health care
  • Substance use
  • Mental health issues

Completion of therapy among persons who have experienced homelessness or been incarcerated can be particularly challenging due to difficulty locating patients for follow-up care and treatment, but is particularly important because of the risk of transmission at shelters or correctional facilities.

Figure 7. Percentage of Newly Diagnosed TB Cases Completing Treatment ≤ 12 Months, U.S., 2018

Figure 7. Percentage of Newly Diagnosed TB Cases Completing Treatment ≤12 Months, United States, 2018

There are several ways to increase treatment completion. These include:

  • Directly observed therapy (i.e., patients are observed to ingest each dose of anti-TB medications)
  • Use of incentives and enablers (e.g., gift cards for food or bus fare for transportation to get to and from the health department) to get patients to complete treatment
  • Promoting the shortest appropriate treatment regimen for each patient

TB treatment is complex and can take several months to complete. It can take up to 2 years to have full treatment information reported for each TB patient. As a result, the most recent information available on completion of therapy is from patients in the 50 states and 9 cities who were identified with TB in 2018.

For these patients, 13 states met or exceeded the 2025 national target of 95.0% of TB cases completing a full treatment regimen in 12 months or less; 14 states and 5 cities were short of the 2025 target but met or exceeded the national average (89.1%) (Figure 7).

Additionally, in 2018 there were 10 states and 6 cities that reported more than 6 TB patients ages 15 years or older who experienced homelessness in the year prior to diagnosis; 7 of these 16 jurisdictions exceeded the national average of 80.6% completion of therapy among TB patients who experienced homelessness (Table 1).

There were 5 states and 4 cities in 2018 that reported more than 4 TB patients ages 15 years or older who were residents of correctional facilities at TB diagnosis; 4 of these 9 jurisdictions exceeded the national average of 72.6% completion of therapy among TB patients residing at correctional facilities (Table 2).

Table 1. Treatment Completion within 12 Months or Less among Newly Diagnosed TB Patients Age ≥15 who Experienced Homelessness within the Year Prior to Diagnosis, United States, 2018

States with 1 to 3 TB patients age ≥ 15 who were homeless
States* with 1 to 3 TB patients age ≥ 15  experiencing homelessness Percentage of patients age >15 experiencing homelessness who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months
Delaware 100.0 83.3
Maryland 100.0 77.4
Missouri 100.0 74.2
New Hampshire 100.0 100.0
North Dakota 100.0 81.8
Philadelphia 100.0 72.3
Alaska 100.0 93.0
Connecticut 100.0 100.0
Pennsylvania 100.0 91.7
Utah 100.0 100.0
Wisconsin 100.0 85.7
Colorado 100.0 96.6
Hawaii 100.0 94.1
Massachusetts 100.0 81.7
Michigan 100.0 95.3
Oregon 100.0 95.8
Oklahoma 66.7 94.8
Baltimore 50.0 77.8
Kansas 0.0 73.9
Kentucky 0.0 85.1
Virginia 0.0 94.0
States with 1 to 3 TB patients age ≥ 15 who were homeless
States* with 4 to 6 TB patients age ≥15 experiencing homelessness Percentage of patients age ≥15 experiencing homelessness who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months
Indiana 100.0 95.8
New York 100.0 95.7
Ohio 100.0 85.9
South Carolina 100.0 93.4
Illinois 100.0 90.1
Nevada 100.0 100.0
Washington 100.0 94.1
Louisiana 83.3 75.8
Alabama 80.0 85.2
New Mexico 80.0 91.2
Maine 75.0 84.6
Minnesota 75.0 92.1
States with 8 or more TB patients age ≥ 15 who were homeless
States* with 7 or more TB patients age ≥15 experiencing homelessness Percentage of  patients age ≥15 experiencing homelessness who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months
Florida 100.0 97.2
Arizona 90.0 85.1
Tennessee 88.9 92.6
New Jersey 87.5 91.7
Mississippi 85.7 93.8
Texas 82.8 84.1
North Carolina 81.8 86.5
California 80.0 88.0
San Francisco 75.0 90.0
San Diego 75.0 85.3
Georgia 72.7 92.8
Houston 57.1 90.4
New York City 57.1 93.1
Los Angeles 55.6 89.6
Arkansas 42.9 76.8
Chicago 42.9 88.2

Table 2. Treatment Completion within 12 Months or Less among Newly Diagnosed TB Patients Age ≥15 who were Incarcerated at the Time of Diagnosis, United States, 2018

States with 1 to 2 TB patients age > 15 who were incarcerated
States with 1 to 2 TB patients age ≥ 15 who were incarcerated Percentage of incarcerated patients age ≥ 15 who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months†
Chicago 100.0 88.2
Connecticut 100.0 100.0
Illinois 100.0 90.1
Louisiana 100.0 75.8
Minnesota 100.0 92.1
New York 100.0 95.7
Pennsylvania 100.0 91.7
Tennessee 100.0 92.6
Alabama 50.0 85.2
Colorado 50.0 96.6
Michigan 50.0 95.3
Missouri 50.0 74.2
New Mexico 50.0 91.2
San Francisco 50.0 90.0
States with 3 to 4 TB patients age > 15 who were incarcerated
States with 3 to 4 TB patients age ≥ 15 who were incarcerated Percentage of incarcerated patients age ≥ 15 who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months†
Indiana 100.0 95.8
New Jersey 100.0 91.7
Ohio 100.0 85.9
Washington 80.0 94.1
Mississippi 75.0 93.8
North Carolina 75.0 86.5
Massachusetts 60.0 81.7
States with 5 or more TB patients age ≥ 15 who were incarcerated
States with 5 or more TB patients age ≥ 15 who were incarcerated Percentage of homeless patients age ≥ 15 who completed treatment within 12 months^ Percentage of all patients who completed treatment within 12 months†
San Diego 100.0 85.3
Houston 88.9 90.4
Arizona 88.9 85.1
Florida 87.5 97.2
Los Angeles 71.4 89.6
California 70.6 88.0
New York City 57.1 93.1
Georgia 55.6 92.8
Texas 55.6 84.1
Footnotes

Figure 7.  Percentage of Newly Diagnosed TB Cases Completing Treatment ≤12 Months, United States, 2018

The fraction in each parenthesis reports the number of TB patients who completed treatment within 12 months out of the total number of patients who were eligible to complete treatment within 12 months.

States/cities are grouped into thirds based on numbers of TB cases reported in 2017.

Baltimore, DC, DE, IA, ID, KS, ME, MT, ND, NE, NH, NM, RI, SD, UT, VT, WV, WI and WY reported 50 or fewer total TB cases in 2018. Due to the small denominator, data should be interpreted with caution.

Data source: National Tuberculosis Surveillance System as of June 14, 2021

Table 1. Treatment Completion within 12 Months among Newly Diagnosed TB Patients Age ≥15  who Experienced Homelessness within the Year Prior to Diagnosis, United States, 2018

*States/cities are grouped into thirds based on numbers of TB cases among persons experiencing homelessness reported in 2018.

^Among those age >15 years who were eligible to complete treatment within 12 months.

Among all patients of any age who were eligible to complete treatment within 12 months (including those who experienced homelessness in the past year).

Note: DC, IA, ID, MT, NV, RI, SD, VT, WV, WY did not report TB cases among persons age ≥15 experiencing homelessness who were eligible to complete treatment.

Data source: National Tuberculosis Surveillance System as of June 14, 2021

Table 2. Treatment Completion within 12 Months or Less among Newly Diagnosed TB Patients Age ≥15 who were Incarcerated at the Time of Diagnosis, United States, 2018

*States/cities are grouped into thirds based on numbers of incarcerated TB cases reported in 2018.

^Among those age ≥15 years who were eligible to complete treatment within 12 months.

Among all patients of any age who were eligible to complete treatment within 12 months (including those who were incarcerated at diagnosis).

Note: AK, AR, Baltimore, DC, DE, HI, IA, ID, KS, KY, MD, ME, MT, ND, NE, NH, NV, OK, OR, Philadelphia, RI, SC, SD, UT, VA, VT, WI, WV, WY did not report TB cases among incarcerated persons age ≥15 years who were eligible to complete treatment.

Data source: National Tuberculosis Surveillance System as of June 14, 2021