PulseNet: Today and Beyond

For Public Health

Key points

  • PulseNet was established in 1996, and for 30 years has improved the United States food safety systems by connecting foodborne illnesses and detecting outbreaks.
  • Every U.S. state has at least 1 laboratory that uses PulseNet technology and can access databases with over 1 million bacterial DNA fingerprints.

How it impacts lives

Since PulseNet was launched in 1996, over 1 billion pounds of contaminated foods have been recalled in the U.S., and an estimated 270,000 foodborne illnesses are prevented every year from the three most common causes: Salmonella, E. coli, and Listeria.

Every year PulseNet saves at least half a million dollars on medical costs and lost productivity. $1 spent = $70 saved!
Over $500 million is saved each year in medical costs and lost productivity.

Food Industry Changes due to PulseNet

In the early 2000s, PulseNet traced a Salmonella outbreak to raw almonds grown in California. This outbreak prompted regulators to mandate that almonds for sale in the U.S. be pasteurized by fumigation or hot steam to prevent future outbreaks.
Graphic depicting foods PulseNet has made safer.
Foods such as peanut butter, sprouts, leafy greens, and melons have been made safer to eat since PulseNet launched in 1996.

PulseNet has made these foods safer to eat: Peanut butter, sprouts, eggs, tree nuts, poultry products, leafy greens, tomatoes, frozen entrees, lunch meat, spices, and melons.

Priorities

PulseNet strives to be a leader in laboratory technology and public health. CDC scientists, public health laboratories, and clinicians all ensure the bacterial DNA fingerprints needed to identify outbreaks are collected and shared. PulseNet continues to be on the forefront of evolving diagnostic methods, utilizes new technology, and looks for modern ways to harmonize systems and detect outbreaks.

PulseNet continues to use whole genome sequencing (WGS) to detect outbreaks. This tool reveals all the genetic material, or genome, in one efficient process. CDC and PulseNet is expanding the use of WGS in state laboratories, and is currently using this tool to identify outbreaks of foodborne illness associated with Listeria, Campylobacter, E. coli, and Salmonella.

Infographic titled "A Tale of Two Outbreaks" comparing E. coli outbreak detection before and after PulseNet. Before PulseNet, a 1993 outbreak in western states took 39 days to detect and resulted in 726 illnesses and 4 deaths. After PulseNet, a 2002 outbreak in Colorado took 18 days to detect and resulted in 44 illnesses and 0 deaths.
Thanks to PulseNet and the many partnerships domestically, the time it takes to detect foodborne outbreaks has been significantly reduced.

Thanks to PulseNet and the many partnerships domestically, the time it takes to detect foodborne outbreaks has been significantly reduced

PulseNet continues to use whole genome sequencing (WGS) to detect outbreaks. This tool reveals all the genetic material, or genome, in one efficient process. CDC and PulseNet is expanding the use of WGS in state laboratories, and is currently using this tool to identify outbreaks of foodborne illness associated with Listeria, Campylobacter, E. coli, and Salmonella.

What's ahead

Culture-Independent Diagnostic Tests (CIDTs)

CIDTs are new tests that will allow laboratories to detect bacterial DNA fingerprints directly from patient samples. This test method doesn't require growing (culturing) the bacteria in order to properly identify it. Laboratories are increasing the use of CIDTs in order to save costs and identify foodborne illnesses faster. PulseNet is developing advanced methods to detect outbreaks without the need for culture.

Content Source
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
About This Page
Published: September 10, 2026
Updated: August 31, 2026

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: September 8, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.