Causal Agents

Balantidium (=Neobalantidium) (=Balantioides) coli, a large ciliated protozoan, is the only ciliate known to be capable of infecting humans. It is often associated with swine, the primary reservoir host. Recent molecular analyses have suggested the need for taxonomic revision, and it is now sometimes referred to as Neobalantidium coli or Balantioides coli, although this nomenclature has neither been resolved nor widely adopted in the medical community.

Life Cycle

Cysts are the stage responsible for transmission of balantidiasis image . The host most often acquires the cyst through ingestion of contaminated food or water image . Following ingestion, excystation occurs in the small intestine, and the trophozoites colonize the large intestine image . The trophozoites reside in the lumen of the large intestine and appendix of humans and animals, where they replicate by binary fission, during which conjugation may occur image . Trophozoites undergo encystation to produce infective cysts image . Some trophozoites invade the wall of the colon and multiply, causing ulcerative pathology in the colon wall. Some return to the lumen and disintegrate. Mature cysts are passed with feces.

Life cycle image and information courtesy of DPDx.