Key points
- Oropouche virus disease (Oropouche) is a nationally notifiable condition.
- No locally acquired cases of Oropouche have been reported in the United States.
Oropouche virus in the United States
- Before 2024, Oropouche had not been identified in U.S. travelers.
- In late 2023, outbreaks of Oropouche virus were reported in endemic areas with spread into locations where the virus previously had not been documented.
- Beginning in 2024, Oropouche was reported among U.S. travelers returning from areas with outbreaks in the Americas such as Panama and Cuba.
- Oropouche became a nationally notifiable condition in early 2025. Cases are reported to CDC by state and local health departments using standardized case definitions.
- Locally acquired Oropouche cases have not been reported from U.S. states or territories.
Oropouche cases by year
2026 U.S. Oropouche cases* reported to ArboNET
Data are preliminary and subject to change. Data are current as of June 16, 2026.
| Year | US States Locally acquired |
US States Travel-associated† |
US Territories Locally acquired |
US Territories Travel-associated |
|---|---|---|---|---|
| 2026 | 0 | 0 | 0 | 0 |
*Includes confirmed and probable disease cases
†Includes cases acquired through other routes (e.g., laboratory transmission)
Historic U.S. Oropouche cases* reported to ArboNET, 2024-2025
The 2025 data are preliminary and subject to change. Data are current as of June 2, 2026.
| Year | US States Locally acquired |
US States Travel-associated† |
US Territories Locally acquired |
US Territories Travel-associated |
|---|---|---|---|---|
| 2024 | 0 | 108 | 0 | 0 |
| 2025 | 0 | 2 | 0 | 0 |
*Includes confirmed and probable disease cases
†Includes cases acquired through other routes (e.g., laboratory transmission)
Limitations of ArboNET data
Surveillance data have several limitations that should be considered when using and interpreting the data.
- Under-reporting is a limitation common to all surveillance systems that rely on healthcare providers to consider the disease as a possible diagnosis in a patient, obtain the appropriate laboratory test, and report confirmed to public health authorities.
- Surveillance data are reported by county of residence, not the location (county or state) of exposure.
- There is a lag in case reporting to CDC and states and territories may publish surveillance data on different schedules than CDC.