About Chemical Disinfectants and Sterilants and Reproductive Health

For Everyone

Key points

  • Chemical disinfectants are used to kill microbes.
  • High level disinfectants (HLDs) are different from disinfectants used at home.
  • HLDs are mostly used on medical equipment that cannot withstand high heat.
  • We do not know whether long-term HLD exposure poses reproductive risks.
Healthcare worker wearing PPE

Understanding chemical disinfectants

Two women work in a hospital as medical hygiene technicians dressed in protective clothing.
High level disinfectants (HLDs) are different from disinfectants used at home.

Chemical disinfectants/sterilants are used to kill bacteria, viruses, fungi, protozoans, and parasites on equipment that cannot be sterilized using high heat.

High-level disinfectants are not the same as most common household disinfectants.

Common household disinfectants include surface sprays and wipes containing quaternary ammonium compounds or sodium hypochlorite (bleach) solutions. Common household disinfectants used by adults according to directions are generally not considered hazardous.

High-level disinfectants are used on delicate equipment that cannot be sterilized with heat. For example, they may be used on medical equipment in healthcare settings. Examples of high-level disinfectants include ethylene oxide gas, hydrogen peroxide gas plasma, glutaraldehyde, orthophthalaldehyde, peracetic acid, and formaldehyde.

Why I should be concerned about exposure to HLDs

Some studies showed a higher risk of reduced fertility, miscarriages, and preterm birth with healthcare workers who were exposed to HLDs.

We don't know what levels of HLD exposure are safe for a pregnant woman, or someone trying to become pregnant.

Who is at risk

  • Healthcare workers
  • Hospital staff
  • Veterinary workers
  • Nail, hair, and beauty salon workers

What I can do to reduce or eliminate exposure

Learn more about best practices recommended for using the specific HLDs used in your workplace:

Resources

Getting help

Talk to your employer or workplace’s safety officer about how to handle HLDs safely at work.

For information on the Pregnant Workers Fairness Act, please see resources from the U.S. Equal Employment Opportunity Commission (EEOC) website.

Talk to your doctor about potential hazards at work. Make sure to mention that your job exposes you to HLDs.

Where I can get more information

NIOSH Hazard Communication for Disinfectants Used Against Viruses

Content Source
National Institute for Occupational Safety and Health
About This Page
Published: May 15, 2024
Updated: October 28, 2026

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: April 3, 2024

The information on this page was last reviewed by subject matter experts to ensure accuracy.