NIOSH Alert: Preventing Adverse Health Effects from Exposure to Dimethylformamide (DMF)

The National Institute for Occupational Safety and Health (NIOSH) requests assistance in reducing the health risks to workers exposed to the solvent dimethylformamide (DMF). This substance is readily absorbed through the skin and is known to be toxic to the liver; recent evidence shows that liver damage may occur in exposed workers who appear to be healthy. DMF is also known to cause skin problems and alcohol intolerance. Some reports also suggest an increase in cancer among workers exposed to DMF, but the evidence is not conclusive at this time. NIOSH and other organizations are working to determine whether exposure to DMF increases the risk of developing cancer.