Immediately Dangerous to Life or Health (IDLH) Value Profile: Hydrogen Chloride CAS® No. 7647-01-0

DHHS (NIOSH) Publication Number 2025-110, Revised June 2025
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This technical report presents the scientific basis, toxicologic data, and risk assessment meth­odology used to derive a health-based immediately dangerous to life or health (IDLH) value for hydrogen chloride (CAS No. 7647-01-0). The IDLH values are based on the scientific rationale and logic outlined in the Current Intelligence Bulletin (CIB) 66: Derivation of Immediately Dangerous to Life or Health Values.

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Suggested citation

NIOSH [2025]. Immediately dangerous to life or health (IDLH) value profile: hydrogen chlo­ride, CAS® No. 7647-01-0. By Frank E, Chittiboyina S, Leshner M, Edmondson M, Niemeier RT. Cincinnati, OH: U.S. Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2025-110 (Revised 06/2025).

List of Revisions
Revision Date Revisions Citation of Revision
May 2025 (Original) NIOSH [2025]. Immediately dangerous to life or health (IDLH) value profile: hydrogen chloride, CAS® No. 7647-01-0. By Frank E, Chittiboyina S, Edmondson M, Niemeier RT. Cincinnati, OH: U.S. Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2025-110.
June 2025

Updated authorship and acknowledgements.

NIOSH [2025]. Immediately dangerous to life or health (IDLH) value profile: hydrogen chlo­ride, CAS® No. 7647-01-0. By Frank E, Chittiboyina S, Leshner M, Edmondson M, Niemeier RT. Cincinnati, OH: U.S. Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2025-110 (Revised 06/2025).