About Project Firstline

CDC’s National Training Collaborative for Healthcare Infection Prevention & Control
4 headshots in multicolored square boxes

CDC’s Project Firstline is a collaborative of diverse healthcare and public health partners that aims to provide engaging, innovative, and effective infection control training for millions of frontline U.S. healthcare workers as well as members of the public health workforce.

Project Firstline’s innovative content is designed so that—regardless of a healthcare worker’s previous training or educational background— they can understand and confidently apply the infection control principles and protocols necessary to protect themselves, their facility, their family, and their community from infectious disease threats, such as COVID-19.

Key Features

Project Firstline reaches healthcare workers in a variety of healthcare settings, including:

  • hospitals,
  • outpatient clinics,
  • dialysis centers, and
  • nursing homes

Project Firstline training materials and educational activities help to empower healthcare workers in building their foundational knowledge of infection control.



Core Training to address immediate workforce infection control training needs, delivered via short and accessible training videos.

Practical Tools to support everyone working in a healthcare facility as they implement infection control protocols and procedures throughout their workday.



Partner Engagement to share information across all healthcare settings through trusted partners and channels, ensuring that training content and tools are delivered to healthcare workers who need them.

Mentorship to connect infection control experts with their local healthcare community so that they may become an ongoing resource.

Lasting Results


Public Health Technical Capacity Building to leverage the public health workforce to facilitate knowledge and tool sharing between public health departments and their local clinical communities.

Innovation to deepen knowledge to better inform infection control recommendations. Project Firstline develops innovative content to provide infection control training to a diverse range of adult learners.