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Hepatitis B Vaccination of Infants, Children, and Adolescents

Infant being immunized

The Advisory Committee on Immunization Practices (ACIP) recommends administration of hepatitis B vaccine and hepatitis B immune globulin (HBIG) for infants born to HBV-infected women within 12 hours of birth, followed by completion of the vaccine series and postvaccination serologic testing; universal hepatitis B vaccination within 24 hours of birth, followed by completion of the vaccine series; and vaccination of children and adolescents aged <19 years who have not been vaccinated previously.

Guidance for Completing the Hepatitis B Series during a Recombivax HB® Shortage: 2018 [PDF – 4 pages]
This document includes clinical considerations and sample schedules for completing the hepatitis B series for children using single-component and combination vaccine products during the Recombivax HB shortage.”

Guidelines and Recommendations

Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices
MMWR Recommendations and Reports / January 12, 2018 / 67(1);1–31

Related Articles:
Update: Shortened Interval for Postvaccination Serologic Testing of Infants Born to Hepatitis B-Infected Mothers
MMWR 2015;64(39);1118-20

Newborn Hepatitis B Vaccination Coverage Among Children Born January 2003–June 2005 — United States
MMWR 2008;57(30):825-828

Implementation of Newborn Hepatitis B Vaccination — Worldwide, 2006
MMWR 2008;57(46);1249-1252

Immunization Schedules and Dosages

Childhood and Adolescent Immunization Schedules

Immunization schedules for all childhood and adolescent vaccines, available in multiple formats

Recommended doses of Hepatitis B vaccines (by age group and vaccine type)

Standing Orders

Nursery nurse and baby

Guidelines for Standing Orders in Labor & Delivery & Nursery Units to Prevent Hepatitis B Virus (HBV) Transmission to Newborns [PDF – 2 pages]
Standing Orders for Administering Hepatitis B Vaccine to Children and Teens [PDF – 1 page]

State Vaccination Requirements

Hepatitis B Vaccination Requirements for Day Care and School, by State

Related Pages

Hepatitis B Vaccination, Screening, and Linkage to Care: Best Practice Advice From the American College of Physicians and CDC
Vaccines and Immunizations