Resources for Laboratorians

2019 Guidelines Update

On June 25, 2019, the American College of Obstetricians and Gynecologists released updated guidance for prevention of early-onset group B Streptococcus (GBS) disease in newborns. On July 8, 2019, the American Academy of Pediatrics released a new clinical report for management of infants at risk for GBS disease. All GBS prevention guidance found on CDC’s website pertains to the 2010 guidelines only. The American Society of Microbiology is currently reviewing GBS laboratory guidance. In the meantime, microbiologists should continue to follow the guidance included in the 2010 GBS guidelines.

2010 Guidelines


Questions and Answers Relevant to Laboratorians





Drug Resistance

The widespread use of intrapartum antibiotic prophylaxis to prevent early-onset group B strep disease has raised concern about the development of antibiotic resistance among group B strep isolates. Learn more about testing for group B strep isolates for antimicrobial susceptibility.


Slide Sets


Clinical Overview


Standard Operating Procedures for 2010 Guidelines for Laboratorians

Standard operating procedures, developed by the American Society for Microbiology (ASM) and CDC’s Streptococcus Laboratory, are available to assist laboratorians in processing group B Streptococcus specimens. The five documents are consistent with the recommendations in the 2010 GBS guidelines, but are tailored for use in different settings, depending on the procedures and assays used in each laboratory (e.g. pigmented or non-pigmented broth, sub-culture versus serologic or molecular methods, etc.).

Note: The Word documents can be modified to adapt for use in individual laboratories. The PDFs are provided simply for Section 508 accessibility.

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