At a glance
- Report possible or confirmed cases of C. auris immediately.
- There are no phenotypic characteristics to easily distinguish C. auris from other Candida species.
- The most reliable way to identify C. auris is MALDI-TOF MS.
- Real-time PCR is the preferred method for detecting colonization.
Laboratory processes and resources
Report possible or confirmed cases
Early detection of C. auris is critical to limiting its spread. Report any possible or confirmed cases immediately to the facility's infection control and prevention department. Follow facility processes for reporting to the state or local public health department.
Safety Guidelines for Working with C. auris isolates
Confirming C. auris
There are no phenotypic characteristics that can easily distinguish C. auris from other Candida species. The most reliable way to identify C. auris is matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). There are several alternative methods to identify C. auris.
Real-Time PCR Based Identification
Procedure for Isolation of C. auris
Antifungal susceptibility testing
All C. auris isolates should undergo antifungal susceptibility testing following Clinical and Laboratory Standards Institute (CLSI) guidelines. Breakpoints are defined based on those established for closely related Candida species and on expert opinion.
Antifungal Susceptibility Testing for C. auris
Surveillance
Healthcare facilities are encouraged to begin screening patients for C. auris after the initial case is identified. Typically skin swab specimens are tested. There are several methods to detect colonization but Real-time PCR is preferred.
Guidance for Detection of C. auris Colonization