For Healthcare Providers

Bourbon virus is a novel RNA virus in the genus Thogotovirus (family Orthomyxoviridae) that was discovered in Bourbon County, Kansas in 2014.


There have been a limited number of Bourbon virus disease cases identified in the United States. Most patients reported exposure to ticks before becoming ill.

Clinical Signs and Symptoms

Patients with Bourbon virus have reported fever, fatigue, anorexia, nausea, vomiting, and maculopapular rash. They were also found to have thrombocytopenia and leukopenia. Based on the patient’s clinical signs and symptoms, they were thought to have a tickborne disease. Some of the patients found to be infected with Bourbon virus have died during their acute illness.

Treatment and Outcome

Currently there are no specific medications or therapies for Bourbon virus disease. Supportive therapy is recommended for any patient suspected of having Bourbon virus disease.


Molecular and serologic testing for Bourbon virus infection can be performed at the CDC. There are no commercially available tests for Bourbon virus infection in the United States. Please contact your state health department if you have a patient with an acute illness that might be compatible with Bourbon virus infection.