What Causes Blastomycosis

For Everyone

Key points

  • Blastomycosis is a lung infection caused by breathing in fungal spores from Blastomyces.
  • Blastomyces live in soil in the midwestern, south-central, and southeastern U.S.
  • Surveillance research helps estimate areas where Blastomyces live.
  • The exact geographic range of the fungus is not known.
  • There are no reliable environmental tests for Blastomyces.
woman and man digging around a tree. They are wearing long sleeves and pants and gloves

Causes

People can get blastomycosis by breathing in Blastomyces, a fungus. The fungus lives in the environment in moist soil and decomposing plant matter like wood and leaves. About half of people who breathe in Blastomyces do not get sick with blastomycosis.

In the United States, the fungus mainly lives in the midwestern, south-central, and southeastern states. It is most common around the Ohio and Mississippi River valleys, Great Lakes, Saint Lawrence River, and western United States. The fungus also lives in Canada and a small number of blastomycosis cases have been reported from Africa and India.

Estimated areas with Blastomyces

These maps show estimates of where the fungus that cause blastomycosis lives.

  • Blastomyces is not evenly distributed within the estimated areas.
  • The fungus may be present outside of the areas shown.
Map with a dark teal indicating the part of the United States where Blastomyces are more likely to live and a light teal shows where they potentially live.
Blastomyces may be found in the soil in much of eastern U.S.
Map showing approximate area with the presence of Blastomyces in the US
Blastomyces have been found most consistently in North America and sporadically in parts of Africa and Asia.

Life cycle facts

Blastomyces lives in the environment as a mold that produces fungal spores. The spores are too small to see without a microscope. When soil or plant material is disturbed, the tiny spores can be released into the air. When people or animals breathe in the spores, they are at risk for developing blastomycosis.

After the spores enter the lungs, the body temperature allows the spores to transform into yeast. The yeast can stay in the lungs or spread through the bloodstream to other parts of the body, such as the skin, bones and joints, organs, and central nervous system (brain and spinal cord).

Diagram showing where Blastomyces live, and how the spore turn to yeast when inhaled and causing infection
Blastomycosis is caused by breathing in Blastomyces spores that turn to yeast remaining in the lung or spreading to other parts of the body.

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Environmental testing

Testing the environment for Blastomyces is unlikely to be useful in most situations. When an environmental sample tests positive for Blastomyces, it isn't necessarily a source of infection, and when a sample tests negative, that doesn't necessarily mean that the fungus isn't there. There are no publicly available tests to detect Blastomyces in the environment. Testing environmental samples for Blastomyces is currently only done for scientific research.

Content Source
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
About This Page
Published: May 15, 2024
Updated: April 24, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: October 27, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.