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Warfarin

Synonyms & Trade Names
3-(α-Acetonyl)-benzyl-4-hydroxycoumarin, 4-Hydroxy-3-(3-oxo-1-phenyl butyl)-2H-1-benzopyran-2-one, WARF
CAS No.
81-81-2
RTECS No.
GN4550000
DOT ID & Guide
Formula
C19H16O4
Conversion
IDLH
100 mg/m3
See: 81812
Exposure Limits
NIOSH REL
: TWA 0.1 mg/m3
OSHA PEL
: TWA 0.1 mg/m3
Measurement Methods

NIOSH 5002
See: NMAM or OSHA Methods
Physical Description
Colorless, odorless, crystalline powder. [Note: Rodenticide.]
MW:
308.3
BP:
Decomposes
MLT: 322°F
Sol:
0.002%
VP(71°F): 0.09 mmHg
IP:
?
Sp.Gr:
?
Fl.P:
?
UEL:
?
LEL:
?
Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
hematuria (blood in the urine), back pain; hematoma arms, legs; epistaxis (nosebleed), bleeding lips, mucous membrane hemorrhage; abdominal pain, vomiting, fecal blood; petechial rash; abnormal hematologic indices
Target Organs
Blood, cardiovascular system
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: No recommendation
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH/OSHA

Up to 0.5 mg/m3:
(APF = 5) Any quarter-mask respirator.
Click here for information on selection of N, R, or P filters.

Up to 1 mg/m3:
(APF = 10) Any particulate respirator equipped with an N95, R95, or P95 filter (including N95, R95, and P95 filtering facepieces) except quarter-mask respirators. The following filters may also be used: N99, R99, P99, N100, R100, P100.
Click here for information on selection of N, R, or P filters.
(APF = 10) Any supplied-air respirator

Up to 2.5 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with a high-efficiency particulate filter.

Up to 5 mg/m3:
(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter.
Click here for information on selection of N, R, or P filters.
(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and a high-efficiency particulate filter
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Up to 100 mg/m3:
(APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter.
Click here for information on selection of N, R, or P filters.
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION   See ICSC CARD: 0821   See MEDICAL TESTS: 0242
 
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