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Coumarin, 3 - (alpha - acetonylbenzyl) - 4 - hydroxy -

RTECS #: GN4550000

CAS #: 81-81-2


UPDATE: May 2009 MW: 308.35 MF: C19H16O4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. (Phenyl - 1 acetyl - 2 ethyl) 3 - hydroxy - 4 coumarine (French)
  2. 1 - (4' - Hydroxy - 3' - coumarinyl) - 1 - phenyl - 3 - butanone
  3. 2H - 1 - Benzopyran - 2 - one, 4 - hydroxy - 3 - (3 - oxo - 1 - phenylbutyl) - (9CI)
  4. 3 - (1' - Phenyl - 2' - acetylethyl) - 4 - hydroxycoumarin
  5. 3 - (Acetonylbenzyl) - 4 - hydroxycoumarin
  6. 3 - (alpha - Acetonylbenzyl) - 4 - hydroxycoumarin
  7. 3 - (alpha - Phenyl - beta - acetylaethyl) - 4 - hydroxycumarin (German)
  8. 3 - (alpha - Phenyl - beta - acetylethyl) - 4 - hydroxycoumarin
  9. 4 - Hydroxy - 3 - (3 - oxo - 1 - fenyl - butyl) cumarine (Dutch)
  10. 4 - Hydroxy - 3 - (3 - oxo - 1 - phenyl - butyl) - cumarin (German)
  11. 4 - Hydroxy - 3 - (3 - oxo - 1 - phenylbutyl) - 2H - 1 - benzopyran - 2 - one
  12. 4 - Idrossi - 3 - (3 - oxo - 1 - fenil - butil) - cumarine (Italian)
  13. Arab Rat Deth
  14. Athrombin - K
  15. Athrombine - K
  16. Brumolin
  17. CO - Rax
  18. Compound 42
  19. Coumadin
  20. Coumafen
  21. Coumafene
  22. Coumarins
  23. Coumefene
  24. Cov - R - Tox
  25. Dethmor
  26. Dethnel
  27. Eastern states duocide
  28. Fasco fascrat powder
  29. Kumader
  30. Kumadu
  31. Kypfarin
  32. Latka 42 (Czech)
  33. Liqua - tox
  34. Mar - frin
  35. Martin's mar - frin
  36. Maveran
  37. Mouse pak
  1. RCRA waste number P001
  2. Rat & mice bait
  3. Rat - B - gon
  4. Rat - Gard
  5. Rat - Kill
  6. Rat - Mix
  7. Rat - O - cide #2
  8. Rat - Trol
  9. Rat - ola
  10. Ratorex
  11. Ratoxin
  12. Ratron
  13. Ratron G
  14. Rats - No - More
  15. Rattunal
  16. Ro - Deth
  17. Rodafarin
  18. Rodex blox
  19. Rough & ready mouse mix
  20. Solfarin
  21. Spray - trol brand roden - trol
  22. Temus W
  23. Twin light rat away
  24. Vampirinip II
  25. Vampirinip III
  26. W.A.R.F. 42
  27. Warf compound 42
  28. Warfarat
  29. Warfarin
  30. Warfarin (ACGIH:OSHA)
  31. Warfarin Q
  32. Warfarin plus
  33. Warfarine (French)
  34. Warficide
  35. Zoocoumarin (Russian)
  36. d - Con


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intramuscular
rabbit
lowest published toxic dose: 10 mg/kg (8-28 day pregnant) Reproductive: Other developmental abnormalities

Reproductive: Effects on newborn: Stillbirth
BLOOAW 36,623,1970
intramuscular
woman
lowest published toxic dose: 12 mg/kg (27-31 week pregnant) Reproductive: Effects on embryo or fetus: Fetal death JMSHAO 26,562,1959
intravenous
mouse
lowest published toxic dose: 240 mg/kg (2-3 day pregnant) Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea) CCPTAY 3,279,1971
oral
woman
lowest published toxic dose: 28 mg/kg (1-20 week pregnant) Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
ADCHAK 55,139,1980
oral
woman
lowest published toxic dose: 8,400 g/kg (1-8 week pregnant) Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue) AJOGAH 127,191,1977
oral
woman
lowest published toxic dose: 33,600 g/kg (1-32 week pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system

Reproductive: Specific developmental abnormalities: Respiratory system

Reproductive: Effects on newborn: Physical
AJOGAH 127,191,1977
oral
woman
lowest published toxic dose: 980 mg/kg (98-168 day pregnant) Reproductive: Effects on embryo or fetus: Fetal death

Reproductive: Specific developmental abnormalities: Blood and lymphatic systems (including spleen and marrow)
JKMSEH 18,764,2003
unreported route
woman
lowest published toxic dose: 6,450 g/kg (27-33 week pregnant) Reproductive: Effects on embryo or fetus: Fetal death JMSHAO 26,562,1959


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lethal concentration (50 percent kill): 320 mg/m3 N/R GTPZAB 22(7),49,1978
intraperitoneal
mouse
lethal dose (50 percent kill): 750 mg/kg N/R EJMCA5 30,531,1995
intraperitoneal
rat
lowest published lethal dose: 420 mg/kg N/R TXAPA9 1,156,1959
intravenous
mouse
lethal dose (50 percent kill): 165 mg/kg N/R 27ZIAQ -,274,1973
oral
cat
lethal dose (50 percent kill): 6 mg/kg N/R DEVEAA 32,27,1978
oral
chicken
lethal dose (50 percent kill): 942 mg/kg Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Lung, Thorax, or Respiration: Dyspnea

Blood: Hemorrhage
BECTA6 37,544,1986
oral
dog
lethal dose (50 percent kill): 3 mg/kg N/R DEVEAA 43(255-256),20,1989
oral
guinea pig
lethal dose (50 percent kill): 180 mg/kg N/R DEVEAA 32,27,1978
oral
human
lowest published lethal dose: 6,667 g/kg N/R YKYUA6 28,329,1977
oral
man
lowest published toxic dose: 10,200 g/kg Blood: Hemorrhage CMEP** -,1,1956
oral
mouse
lethal dose (50 percent kill): 3 mg/kg N/R DEVEAA 43(255-256),20,1989
oral
pig
lethal dose (50 percent kill): 1 mg/kg N/R DEVEAA 32,27,1978
oral
rat
lethal dose (50 percent kill): 1,600 g/kg N/R TXAPA9 11,327,1967
oral
rabbit
lethal dose (50 percent kill): 800 mg/kg N/R DEVEAA 32,27,1978
oral
woman
lowest published toxic dose: 250 g/kg/2 day- intermittent Vascular: Structural changes in vessels AJEMEN 16,541,1998
oral
woman
lowest published toxic dose: 15 mg/kg/21 week- intermittent Gastrointestinal: Ulceration or bleeding from small intestine

Blood: Change in clotting factors
SMJOAV 75,242,1982
subcutaneous
mouse
lowest published lethal dose: 800 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)
TIVSAI 58,122,1977
skin
rat
lethal dose (50 percent kill): 1,400 mg/kg Eye: Chromodacryorrhea

Behavioral: Muscle weakness

Kidney, Ureter, and Bladder: Hematuria
GTPZAB 22(7),49,1978
skin
rat
lowest published toxic dose: 50 g/kg Biochemical: Metabolism (intermediary): Lipids including transport

Biochemical: Metabolism (intermediary): Other proteins

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXCYAC 212,206,2005
unreported route
mouse
lethal dose (50 percent kill): 60 mg/kg N/R YKYUA6 30,397,1979
unreported route
rat
lethal dose (50 percent kill): 50 mg/kg N/R YKYUA6 30,397,1979


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 16 mg/m3/4 hour/30 day- intermittent Blood: Normocytic anemia

Blood: Changes in erythrocyte (RBC) count

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
GTPZAB 22(7),49,1978
intraperitoneal
rat
lowest published toxic dose: 10 mg/kg/2 day- intermittent Liver: Other changes

Blood: Change in clotting factors
TXAPA9 180,186,2002
intraperitoneal
rat
lowest published toxic dose: 0.3 mg/kg/3 day- intermittent Nutritional and Gross Metabolic: Changes in: K TOXID9 44,106,2005
intraperitoneal
rat
lowest published toxic dose: 20 mg/kg/2 day- intermittent Liver: Other changes TXCYAC 225,128,2006
oral
dog
lowest published toxic dose: 12 mg/kg/6 day- intermittent Blood: Change in clotting factors

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
YKYUA6 31,1385,1980
oral
human
lowest published toxic dose: 4.35 mg/kg/15 day- intermittent Blood: Hemorrhage HBPTO* 1,60,2001
oral
mammal (species unspecified)
lowest published toxic dose: 686 mg/kg/28 day- continuous Behavioral: Food intake (animal)

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
AECTCV 16,357,1987
oral
pig
lowest published toxic dose: 1 mg/kg/5 day- intermittent Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Blood: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferases
AJVRAH 43,1387,1982
oral
rat
lowest published toxic dose: 11,250 g/kg/90 day- intermittent Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) TOLED5 1000(Suppl 1),141,1980
oral
rat
lowest published toxic dose: 17,800 g/kg/10 day- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field ESDBAK 32,251,1981
oral
rat
lowest published toxic dose: 3.2 mg/kg/40 day- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field HBPTO* 1,60,2001
oral
rat
lowest published toxic dose: 275.2 mg/kg/4 day- continuous Behavioral: Food intake (animal)

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
VHTODE 43,327,2001


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.1 mg/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
TJADAB 66,127,2002
TOXICOLOGY REVIEW
BJOPAL 64,633,1980
TOXICOLOGY REVIEW
AJHGAG 30,104A,1978
TOXICOLOGY REVIEW
AJMEAZ 68,122,1980
TOXICOLOGY REVIEW
MUREAV 488,151,2001
TOXICOLOGY REVIEW
TPHSDY 23,358,2002
TOXICOLOGY REVIEW
EMMUEG 43,143,2004
TOXICOLOGY REVIEW
TPHSDY 24,589,2003
TOXICOLOGY REVIEW
APHRER 38,99,2004
TOXICOLOGY REVIEW
APHRER 38,2115,2004
TOXICOLOGY REVIEW
AUIMR* 1,183,2002
TOXICOLOGY REVIEW
DIMON* 40,258,1994
TOXICOLOGY REVIEW
DIMON* 39,678,1993
TOXICOLOGY REVIEW
ENTOX* -,461,2005
TOXICOLOGY REVIEW
APHRER 40,2101,2006
TOXICOLOGY REVIEW
MJAUAJ 178,413,2003
TOXICOLOGY REVIEW
HUTOX* -,561,1996
TOXICOLOGY REVIEW
HUTOX* -,561,1996


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: RED Completed RBREV* -,156,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.1 mg/m3 DTLVS* 3,279,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.1 mg/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.1 mg/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.1 mg/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.1 mg/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.1 mg/m3, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.1 mg/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.1 mg/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.1 mg/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 0.1 mg/m3, short term exposure limit 0.3 mg/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 mg/m3, FEB2006
Occupational Exposure Limit - GERMANY MAK 0.5 mg/m3 (inhalable), 2005
Occupational Exposure Limit - KOREA time-weighted average 0.1 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.1 mg/m3;
short term exposure limit 0.3 mg/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.1 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.1 mg/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 0.1 mg/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.1 mg/m3, JAN1993
Occupational Exposure Limit - RUSSIA short term exposure limit 0.001 mg/m3, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 mg/m3,KZG- week 0.2 mg/m3, DEC2006
Occupational Exposure Limit - THAILAND time-weighted average 0.1 mg/m3, JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 0.1 mg/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.1 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.1 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO WARFARIN-air 10 hour time-weighted average 0.1 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 76610;
Number of Industries 3;
Total Number of Facilities 2,535;
Number of Occupations 5;
Total Number of Employees Exposed 26,783
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 76610;
Number of Industries 6;
Total Number of Facilities 446;
Number of Occupations 8;
Total Number of Employees Exposed 6,131;
Total Number of Female Employees Exposed 1,874


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an oral anticoagulant and as a rodenticide
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Warfarin, 5002


REFERENCES:

CODEN
REFERENCE

27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973
ADCHAK Archives of Disease in Childhood. (British Medical Journal, POB 560B, Kennebunkport, ME 04046) V.1- 1926-
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973-
AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983-
AJHGAG American Journal of Human Genetics. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1949-
AJMEAZ American Journal of Medicine. (Technical Pub., 875 Third Ave., New York, NY 10022) V.1- 1946-
AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
AJVRAH American Journal of Veterinary Research. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940-
APHRER Annals of Pharmacotherpy. (Harvey Whitney Books Co., POB 42696, Cincinnati, OH 45242) V. 26- 1992-
AUIMR* Autoimmunity Reviews (Amsterdam ; New York : Elsevier) V.1- 2002-
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966-
BJOPAL British Journal of Ophthalmology. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1917-
BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946-
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947-
DIMON* Disease-a Month (Chicago : Year Book Publishers) V. 24- 1978-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974-
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
ESDBAK Eisei Dobutsu. Sanitary Zoology. (Nippon Eisei Dobutsu Gakkai, c/o Kokuritsu Yobo Eisei Kenkyusho Eisei Konchubo, 2-10-35 Kami-osaki, Shinagawa-ku, Tokyo 141, Japan) V.1- 1950-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
HUTOX*
JKMSEH Journal of Korean Medical Science. (Korean Academy of Medical Science, C.P.O. Box 2062, Seoul, S. Korea) V.1- 1986-
JMSHAO Journal of the Mount Sinai Hospital (New York). (New York, NY) V.1-36, 1934-69. For publisher information, see MSJMAZ.
MJAUAJ Medical Journal of Australia. (Australasian Medical Pub. Co. Ltd., 71-79 Arundel St., Glebe, N.S.W., Australia) V.1- 1914-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
SMJOAV Southern Medical Journal. (Southern Medical Assoc., POB 2446, Birmingham, AL 35205) V.1- 1908-
TIVSAI Trudy, VNIIVS. Transactions of the All-Union Scientific Research Institute of Veterinary Sanitation. (VNIIVS, Moscow, USSR) V.11- 1957-
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
TPHSDY Trends in Pharmacological Sciences. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1979-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977-
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

Used as an oral anticoagulant and as a rodenticide

RTECS Compound Description:
   Agricultural Chemical
   Drug
   Reproductive Effector
   Human Data
   Natural Product

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